头孢哌酮/舒巴坦误用致喉头水肿  

Laryngeal edema due to misuse of cefoperazone/sulbactam

作　　者：任爱民[1] 沈淑凤[1] 张俊霞[1] 

机构地区：[1]北京地坛医院内科,北京100011

出　　处：《药物不良反应杂志》2008年第2期128-128,共1页Adverse Drug Reactions Journal

摘　　要：1例46岁腹水与腹腔感染男性患者未行皮试静脉滴注瑞普欣(头孢哌酮/舒巴坦)3g。1min后出现颜面、颈部潮红,全身瘙痒,口唇舌麻木,呼吸困难,体检显示SPO20.98,BP90/60mmHg,P110次/min,喉镜检查示喉头水肿。经吸氧和对症治疗,1h后症状缓解。该患者半个月前曾使用铃兰欣(头孢哌酮/舒巴坦),出现皮肤瘙痒。A 46-year-old man with ascites and abdominal cavity infection received IV Ruipuxin （cefoperazone/sulbactam）3 g without skin testing. One minute later, the patient developed a flushing in face and neck, generalized pruritus, numbness of the lips and tongue, and dyspnea. An examination revealed the following values： SPO2 0. 98, BP 90/60 mmHg, and P 110 beats/min. Laryngoscopy showed laryngeal edema. Oxygen therapy and symptomatic treatment were given. One hour later, his symptoms resolved. The patient had experienced generalized prupritus after injection of Linglanxin （cefoperazone/sulbactam） a half month before.

关 键 词：头孢哌酮/舒巴坦 喉头水肿 误用 

分 类 号：R595.3[医药卫生—内科学]