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作 者:胡慧霞[1] 郭海波[1] 张永军[1] 汪凡军[1] 罗春梅[1] 魏胜兵[1] 张磊[1] 赵俊红[1] 陈建波[1]
机构地区:[1]广州金域医学检验中心有限公司,广州510330
出 处:《热带医学杂志》2008年第4期378-380,共3页Journal of Tropical Medicine
基 金:广州市科技公关计划(No.2005Z1-E0071)。
摘 要:目的了解广东地区泌尿生殖道支原体感染的情况以及对药物的敏感性。方法采用支原体培养、鉴定、计数及药敏一体化试剂盒对2126例泌尿生殖系感染患者进行检测及药物敏感性试验。结果2126例中支原体阳性1080例,阳性率为50.80%。其中解脲支原体(Uu)、人型支原体(Mh)及解脲和人型支原体(Uu+Mh)混合感染的阳性率分别为37.53%(798例)、2.72%(58例)、10.54%(224例)。Uu对12种抗菌药物敏感性依次是克拉霉素(89.15%)、美满霉素(87.00%)、强力霉素(86.00%)和四环素(81.80%),Mh敏感性较高的依次是强力霉素(95.20%)、美满霉素(95.20%)和交沙霉素(84.10%),Uu+Mh对12种抗生素的敏感性均较差。结论广东地区支原体感染主要以Uu为主,其次是Uu+Mh混合感染;Uu、Mh和Uu+Mh三者对抗生素的敏感性存在一定的差异,临床上应根据支原体培养及药敏试验结果合理用药,以最大限度地控制新耐药菌株的产生。Objective To study the infectious status of Mycoplasma and the antibiotic susceptibility in Guangdong. Method 2126 samples of urinary infection with the diagnosis of urinogenital Mycoplasma were cultured and tested for drug sensitivity. Result 1080 out of 2126 cases (50.80%) were Mycoplasma positive, with U. urealyticum (Uu) positive rate of 37.53 % (798 cases), M.hominis (Mh) of 2.72% (58 cases), and Uu + Mh of 10.54% (224 cases). The results of drug sensitivity showed that Uu was susceptible to clarithromycin (89.15%), minocycline (87.00%), deoxycycline (86.00%) and ambramycin (81.80%); Mh was susceptible to doxycycline (95.20%), minocycline (95.20%) and josamycinto (84.10%), Uu +Mh was resistance to these antibiotics. Conclusion Mycoplasma infection in genitourinary tract is mainly due to Uu infection and mixed infection with Uu and Mh in Guangdong. The antibiotic treatment should be based on drug sensitivity tests to reduce the development of drug-resistant stains.
分 类 号:R375[医药卫生—病原生物学]
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