Comparison of clinical outcomes of frozen-thawed blastocysts transfer in natural and hormonally controlled cycles  

Comparison of clinical outcomes of frozen-thawed blastocysts transfer in natural and hormonally controlled cycles

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作  者:高辉 孙正怡 邓成艳 郁琦 何方方 

机构地区:[1]Department of Obstetrics & Gynecology,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences

出  处:《生殖医学杂志》2007年第A01期79-83,共5页Journal of Reproductive Medicine

摘  要:Objectives:To assess the clinical outcomes of frozen-thawed blastocysts transfer in natural and hormonally controlled cycles.Methods:A retrospective analysis of natural and hormonally controlled cycle for 246 frozen-thawed blastocyst transfer cycles,the clinical pregnancy rate,implantation rate,early abortion rate were compared.Results:Of the 192 hormonally controlled cycles,the cancel rate,clinical pregnancy rate per ET,implantation rate and abortion rate were 7.3%(14/192),53.9%(96/178),38.8%(131/338)and 11.5%(11/96)respectively,whereas in 54 natural cycles,these rates were 16.7%(9/54),68.9%(31/45),52.9%(45/85)and 16.1%(5/31)respectively.There was no significant difference between the two groups with regard to the clinical pregnancy and abortion rate per ET,but the cancel rate and implantation rate were higher in natural cycles.However,the pregnancy and implantation rates of patients without PCOS in hormonal control cycles(57.2%,40.9%)were similar with those in natural cycles(P>0.05).Conclusion:These findings suggested that both hormonally controlled and natural cycles had similar pregnancy outcomes in frozen-thawed blastocysts transfer.Objectives:To assess the clinical outcomes of frozen-thawed blastocysts transfer in natural and hormonally controlled cycles. Methods: A retrospective analysis of natural and hormonally controlled cycle for 246 frozen-thawed blastocyst transfer cycles, the clinical pregnancy rate, implantation rate, early abortion rate were compared. Results: Of the 192 hormonally controlled cycles, the cancel rate, clinical pregnancy rate per ET, implantation rate and abortion rate were 7.3% (14/192), 53.9% (96/178), 38.8% (131/338)and 11.5% (ll/96)respectively, whereas in 54 natural cycles, these rates were 16.7%(9/54), 68.9%(31/45), 52.9%(45/85) and 16.1%(5/31) respectively. There was no significant difference between the two groups with regard to the clinical pregnancy and abortion rate per ET, but the cancel rate and implantation rate were higher in natural cycles. However, the pregnancy and implantation rates of patients without PCOS in hormonal control cycles(57. 2%, 40. 9%) were similar with those in natural cycles(P〉0.05). Conclusion: These findings suggested that both hormonally controlled and natural cycles had similar pregnancy outcomes in frozen-thawed blastocysts transfer.

关 键 词:胚泡 临床分析 生殖功能 孕妇 

分 类 号:R321.3[医药卫生—人体解剖和组织胚胎学] R135.1[医药卫生—基础医学]

 

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