化妆品中7种阴离子的固相萃取-离子色谱测定法  

Simultaneous Determination of Seven Anions in Cosmetic by Suppressed Ion Chromatogram

作　　者：许淑霞[1] 刘丽梅[1] 张勇[1] 汪隽[1] 韩宝武[1] 马小童[1] 

机构地区：[1]成都理工大学材料与化学化工学院,四川成都610059

出　　处：《环境与健康杂志》2008年第2期155-158,共4页Journal of Environment and Health

基　　金：国家地质调查项目(200314200015)

摘　　要：目的建立化妆品中无机阴离子(F-、Cl-、Br-、NO2-、H2PO4-、SO42-、NO3-)的固相萃取-电导离子色谱测定方法。方法化妆品样品经固相萃取柱(SPE)富集、净化后,在aniondual2型阴离子分析柱上,以1.0mmol/LNa2CO3+1.5mmol/LNaHCO3为淋洗液,流量为0.8ml/min,在15min内1次进样测定了7种阴离子。结果F-、Cl-、NO2-、Br-、NO3-、H2PO4-、SO42-的线性范围分别是0.05～3、0.125～7.5、0.125～7.5、0.25～15、0.25～15、2.5～15、0.25～15mg/L,RSD均小于4.0%,样品加标回收率在82.0%～123.0%之间。结论该方法快速、灵敏、准确,可用于化妆品中7种阴离子的同时测定。Objective To develop a suppressed conduction ion chromatography （IC） for simultaneous determination of 7 anions（F^-, Cl^-, Br^-, NO2^-, H2PO4^-, SO^2-4 and NO3^-） in cosmetics. Methods The cosmetics samples were enriched by solid-phase extraction （SPE）. The IC separation was carried out with an anion dual 2 analytical column using 1.0 mmol/L Na2CO3＋1.5 mmol/L NaHCO3 as the mobile phase at a constant flow rate of 0.8 ml/min, then 7 anions could be determined in one injection within 15 min. Results The anions showed good linear relations in a wide range and the recovery rates ranged from 82.0% to 123.0%. The relative standard deviations （RSD） were less than 4.0% and it had been successfully applied to the routine analysis. Conclusion This method is fast, accurate, sensitive and suitable for the analysis of cosmetic samples.

关 键 词：化妆品 色谱法 离子交换 抑制型离子色谱 

分 类 号：O657.7[理学—分析化学]