实验性口腔粘膜炎性损害的抗氧化防治机理研究Ⅰ.口腔粘膜微循环观测  

The Mechanisms of Antioxidantenzyme Against Inflammatory Lesion in Animal Oral Mucosa Ⅰ. An Investigation on Microcirculation in Oral Mucosa

作　　者：周红梅[1] 李秉琦[1] 胡涛[1] 周敏[1] 陈谦明[1] 段开文[1] 

机构地区：[1]华西医科大学口腔医学院口腔粘膜病研究室

出　　处：《华西口腔医学杂志》1997年第4期348-350,共3页West China Journal of Stomatology

基　　金：华西医科大学口腔医学院青年基金

摘　　要：利用氧自由基（ＯＦＲ）诱导的金黄地鼠颊囊急性炎症损害模型，采用活体微循环观察法及透射电镜技术，观测颊囊粘膜微循环的动态变化。结果显示：模型组动物颊囊粘膜微循环出现严重障碍，而ＳＯＤ组的微循环损害却明显减轻。推测ＳＯＤ通过有效清除组织中过量的ＯＦＲ。A technique of vital microcirculation observation and electron microscope were used to study the microcirculation in hamster cheek pouch, in which an acute inflammatory lesion was induced by oxygen free radicals (OFR). At the same time, the effect of superoxide dismutase (SOD) on the microcirculation was assessed. The results showed that in the model group the microcirculation disturbance in the cheek pouch was very serious. However, in the SOD group the microcirculation was almost unchangable.

关 键 词：超氧化物歧化酶 口腔粘膜病 炎症 微循环 

分 类 号：R781.5[医药卫生—口腔医学]