思密达加甲硝唑注射液灌肠治疗重症腹泻60例疗效观察  

Observation on the curative effect of enema with Smecta plus metronidazole injection in the treatment of 60 patients with severe diarrhea

作　　者：陈风娇[1] 张春燕[1] 殷秋阳[1] 

机构地区：[1]聊城市人民医院,山东聊城252000

出　　处：《齐鲁护理杂志（下半月刊）（外科护理）》2008年第4期19-20,共2页Journal of Qilu Nursing

基　　金：聊城市科技局成果登记号:聊科成2007-158

摘　　要：目的:探讨思密达加甲硝唑注射液灌肠治疗重症腹泻患者的疗效。方法:将120例重症腹泻患者随机分为实验组和对照组各60例,实验组采用思密达3g加入40m l甲硝唑注射液,对照组采用思密达3g加入40m l生理盐水,均行保留灌肠,4次/d,连用3d,对两组疗效进行对比分析。结果:实验组和对照组总有效率分别为93.3%、73.3%,皮肤并发症发生率分别为15.0%、36.7%,两组比较均有显著性差异(P<0.05);实验组和对照组平均止泻时间分别为48.00±18.31h、90.00±33.19h,两组比较有极显著性差异(P(0.01)。结论:思密达加甲硝唑注射液灌肠治疗重症腹泻疗效显著,值得临床推广应用。Objective： To explore the curative effect of enema with Smecta plus metronidazole injection in the treatment of severe diarrhea. Methods： One hundred and twenty patients with severe diarrhea were randomly divided into test group and control group （ 60 for each ）. Retention - enema with 3g Smecta plus 40ml metronidazole injection was used in test group and retention - enema with 3 g Smecta plus 40ml normal saline was taken in control group. Retention - enema was given 4 times per day and last 3 days and then the curative effect was compared and analyzed. Results ： The total effective rates were 93.3% and 73.3% and the incidence of skin complications were 15.0% and 36.7% in test and control group respectively （ P 〈 0. 051 - The average antidiarrheal time is 48.00 ± 18.31 hours and 90.00 ＋ 33.19 hours in test group and control group respectively （ P 〈 0. 01 ）. Conclusion： Enema with Smecta and metronidazole injection is very effective in the treatment of severe diarrhea.

关 键 词：思密达 甲硝唑注射液 灌肠 腹泻 

分 类 号：R473.6[医药卫生—护理学]