异甘草酸镁联合丹参治疗慢性乙型肝炎的临床研究  

Clinical Research on treatment of chronic hepatitis B with magnesium isoglycurrhizinate and alvia miltiorrhiza

作　　者：薛育政[1] 刘宗良[1] 陆宇峰[1] 尹群[1] 戴泓[1] 

机构地区：[1]无锡市第三人民医院消化内科,江苏无锡214041

出　　处：《中国中西医结合消化杂志》2008年第2期109-111,共3页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：[目的]观察异甘草酸镁联合丹参治疗慢性乙型肝炎(CHB)的疗效。[方法]治疗组60例,给予异甘草酸镁针剂100 mg加入5%葡萄糖注射液250 ml中静脉滴注,丹参针剂20 ml加入5%葡萄糖注射液250 ml静脉滴注,均1次/d;对照组50例,仅给予异甘草酸镁针剂,剂量、疗法同治疗组,疗程均为6周。治疗结束后对患者症状、体征积分、肝功能及肝纤维化指标进行分析。[结果]2组患者的症状、体征、肝功能及肝纤维化指标恢复均较快,2组比较差异有统计学意义(P<0.05)。[结论]异甘草酸镁联合丹参可明显改善CHB的临床症状、肝功能及肝纤维化指标。[Objective]To observe the clinic effect of magnesium isoglycurrhizinate and salvia miltiorrhiza on chronic hepatitis B（CHB）. [Methods]One hundred and ten patients , who suffer from CHB, were divided into two groups： treatment group and control group. The former were treated by magnesium isoglycurrhizinate （100mg/day） and salvia miltiorrhiza （20ml/day） injection, and the latter were treated by magnesium isoglycurrhizinate （100mg/day）injection. Six weeks was one course of treatment. The scores of symptoms and the hepatic functions, including ALT, AST, Tbil, GGT at the beginning, ending of the treatment were observed. And at the beginning and ending , the hepatic fibrosis index（including PCIII, HA, LN, IV-C） were observed. [Results] After treatment, the patient＇s symptom, sign and index of liver function and hepatic fibrosis were significantly improved. [Conclusion ]Magnesium isoglycurrhizinate combined salvia miltiorrhiza can improve symptom, sign and index of liver function and hepatic fibrosis obviously.

关 键 词：乙型肝炎 慢性 丹参 异甘草酸镁 

分 类 号：R512.6[医药卫生—内科学]