凤尾草颗粒剂治疗良性前列腺增生症的临床疗效评价  

Clinical Evaluation on Fengweicao Granule in Treating Benign Prostatic Hyperplasia

作　　者：薛波新[1] 单玉喜[1] 向贵[2] 王益[2] 刘兆伟[2] 汪意青[2] 邵雪峰[2] 张国庆[3] 颜纯海[1] 

机构地区：[1]苏州大学附属第二医院泌尿外科,江苏215004 [2]江苏省太仓市第一人民医院泌尿外科 [3]苏州大学附属第二医院中医科

出　　处：《中国中西医结合杂志》2008年第5期456-458,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的观察中药凤尾草颗粒剂治疗良性前列腺增生症(BPH)的疗效。方法将155例BPH患者分为中药治疗组(108例)和西药对照组(47例),中药组予凤尾草颗粒剂5g,每天2次口服,西药组予保列治每天5mg顿服,两组均连续用药3个月。观察治疗前后国际前列腺症状评分(I-PSS)、最大尿流率(MFR)、经腹B超测膀胱残余尿量、前列腺体积的变化。结果与治疗前比较,治疗后两组患者的I-PSS评分、MFR及残余尿量均明显改善(P<0.05或<0.01),前列腺体积的改变差异无统计学意义;两组治疗后比较差异亦无统计学意义(P>0.05)。结论中药凤尾草颗粒剂治疗BPH具有较好的疗效,且不良反应少。Objective To report the effect of Fengweicao Granule （FWCG）, a Chinese herbal preparation made of herba Pteris multifidae, in treating benign prostatic hyperplasia （BPH）. Methods One hundred and fifty-five patients were assigned to two groups, the 105 patients in the treated group were administered orally with FWCG twice a day, 5 g every time ; the 47 patients in the control group were treated with Proscar 5 mg per day for 3 months. The effects were evaluated by the change of the related indexes before and after treatment, including scoring by international prostatic symptom scale （ I-PSS）, maximum flowing rate of urine （ MFR）, residue urine volume （RU） in urinary bladder determined by abdominal B-ultrasonography and volume of prostate. Results After being treated for 3 months, the I-PSS, MFR and RU improved remarkably in both groups （P 〈0. 05 or P 〈0. 01 ） ,but with no significant change in the volume of prostate, neither with significant difference in comparison between the two groups （P 〉 0. 05 ）. Conclusion FWCG has a good effect with less adverse reaction in treating BPH.

关 键 词：良性前列腺增生症 风尾草 保列治 中医药 

分 类 号：R277.5[医药卫生—中医学]