减压液相色谱法制备季戊四醇三乙酸酯  

Synthesis of pentaerythritol triacetate by vacuum liquid chromatography

作　　者：张红宇[1] 柳恒[1] 苏天铎[1] 崔荣[1] 

机构地区：[1]西安近代化学研究所,陕西西安710065

出　　处：《应用化工》2008年第5期541-543,共3页Applied Chemical Industry

摘　　要：以季戊四醇和乙酸酐(摩尔比为1∶3)为原料,回流反应,生成季戊四醇一、二、三、四乙酸酯的混合物,用减压液相色谱(VLC)法制备出了纯度为98.5%的季戊四醇三乙酸酯。VLC的吸附剂采用薄层层析用硅胶,硅胶颗粒细,吸附能力强,载样量大。凭借真空的动力加速溶剂的流动。该法操作简便、分离效率高、溶剂用量少、快速省时。Pentaerythritol and acetic anhydride （ mole ratio： 1 ＂3 ） was refluxed to give mono-, di-, tri-and tetraacetate of pentaerythritol. Pentaerythritol triacetate was separated by vacuum liquid chromatography to be 98.5% pure. The adsorbent of vacuum liquid chromatography （VLC） is silica gel of thin-layer chromatography. Which grain is thin, and adsorptive power is strong. So it＇ s load capacity is great. And fluxion of solvent accelerate by motive of vacuum. This method had the advantages of simple process, efficiency, dosage of solvent is little and save time quickly.

关 键 词：季戊四醇三乙酸酯 二季戊四醇缩甲醛 季戊四醇 减压液相色谱法 

分 类 号：TQ223[化学工程—有机化工]