超声化学法合成羟基磷灰石纳米棒  

Sonochemical synthesis of hydroxyapatite nanorods in simulated body fluid

作　　者：李东旭[1] 耿燕丽[1] 李延报[1] 

机构地区：[1]南京工业大学材料科学与工程学院,材料化学工程国家重点实验室,江苏南京210009

出　　处：《功能材料》2008年第5期808-810,共3页Journal of Functional Materials

基　　金：国家自然科学基金资助项目(20573455)

摘　　要：在37℃下的模拟体液中采用超声化学法制备羟基磷灰石（HA）纳米棒，研究了初始PH值和反应时间对合成磷酸钙产物晶相的影响。结果发现在初始pH〈7．5时产物为无水磷酸氢钙相和HA相的混合物，初始pH值≥7.5时产物为单一的HA相，延长超声波处理时间有利于羟基磷灰石晶相的生成，最佳的反应参数为初始pH≥7.5，反应时间在6h以上。利用TEM、FTIR对HA相产物进行表征发现，HA为含碳酸根羟基磷灰石，其形貌长度为200nm，直径为10-30nm的纳米棒，其在组成和形态上与生物体内的磷灰石相十分接近。Hydroxyapatite nanorods were synthesized by sonochemistry in the simulated body fluid solution （SBF） at 37℃. The effects of initial pH in the SBF buffer solution and ultrasonic treating times on the phase composition of calcium phosphate precipitates were investigated by XRD. The results show that monetite and HA phases appeared if initial pH〈7.5, and only pure hydroxyapatite phase can be obtained at pH≥7.5 after ultrasonic treating for more than 6h. Hydroxyapatite is nanosized rods with carbonate substituted and a long/diameter of 200nm/10-30nm, which is very similar to the mineral phase of bone from the viewpoint of chemical composition and morphology.

关 键 词：模拟体液 羟基磷灰石 超声化学 磷酸氢钙 

分 类 号：TP174.1[自动化与计算机技术—控制理论与控制工程] R318.08[自动化与计算机技术—控制科学与工程]