正交试验优选消症贴膏提取工艺  

Optimization of the Extraction Process for Xiaozheng Plaster by Orthogonal Test

作　　者：袁学文[1] 彭汉堪[1] 叶立新[1] 罗玉川[1] 

机构地区：[1]广东惠州市人民医院,惠州市516002

出　　处：《中国药房》2008年第15期1148-1150,共3页China Pharmacy

摘　　要：目的:优选消症贴膏中处方药材的提取工艺。方法:以水提醇沉法提取精制,以水苏碱含量和干浸膏得率为评价指标,通过正交试验优选合理的提取工艺参数。结果:优选的消症贴膏最佳水提工艺为醇沉浓度45%,加12倍量水煎煮3次,每次90min。结论:通过直观分析可以确定提取工艺条件;制剂制备工艺可行。OBJECTIVE： To optimize the extraction process of Xiaozheng plaster, a traditional Chinese medicine. METHODS： Xiaozheng plaster was prepared by water extraction and alcohol precipitation method with stachydrine content in water and the yield of powdered extract as evaluation indexes, The orthogonal test was carried out to optimize the reasonable parameters of the extraction process. RESULTS： The optimal extraction process for the prescription was adding 12-fold of water and decocting for 90 minutes at each time for three times altogether with alcohol precipitation concentration at 45%. CONCLUSION： The extractive condition can be optimized through visual analysis and the preparation technology is feasible.

关 键 词：消症贴膏 提取工艺 正交试验 

分 类 号：R284.2[医药卫生—中药学] R944.21[医药卫生—中医学]