埋针配合药物治疗抑郁症睡眠障碍的临床观察  

Clinical Observations on Treatment of Dyssomnia by Needle Embedding plus SSRIs in Depression Patients

作　　者：王天俊[1] 王玲玲[1] 陶文剑[1] 陈理[1] 

机构地区：[1]南京中医药大学第二临床医学院,南京210029

出　　处：《上海针灸杂志》2008年第5期5-7,共3页Shanghai Journal of Acupuncture and Moxibustion

基　　金：江苏省教育厅自然科学研究计划(03KJA360093)

摘　　要：目的观察埋针配合SSRI类药物治疗抑郁症睡眠障碍对HAMD量表睡眠积分改善的差异以及与治疗频次的关系。方法71例抑郁症患者随机分为三组,埋针组24例,采用埋针配合SSRI类药物治疗;针刺组21例采用针刺配合SSRI类药物治疗;药物组26例单纯给于SSRI类药物治疗。分别观察三组治疗前及治疗1、2、4、6星期后HAMD睡眠积分的差异。结果埋针组和针刺组HAMD睡眠积分的改善显著优于药物组,埋针组和针刺组从治疗第1星期开始就可显著改善睡眠积分,与药物组存在着显著的差异(P<0.01);其后的2、4星期继续保持这种差异,到第6星期时三组已经没有差异。SSRI类药物治疗也可以改善HAMD睡眠积分。结论埋针和针刺配合SSRI类药物均可明显改善抑郁症睡眠障碍,且起效迅速,优于单纯SS-RI类药物治疗。而埋针治疗与针刺治疗比较差异无统计学意义,但由于埋针治疗减少了治疗的频次,有着积极的临床意义。Objective To investigate an improvement in HAMD sleep score and its relationship with treatment frequency in treatment of dyssomnia by needle embedding plus SSRIs in depression patients. Methods Seventy-one depression patients were randomly allocated to three groups. The needle embedding group of 24 cases was treated by needle embedding plus SSRIs, the acupuncture group of 21 cases, by acupuncture plus SSRIs and the medication group of 26 cases, with simple SSRIs. HAMD sleep score was counted in the three groups before treatment and at 1,2, 4 and 6 weeks after. Results HAMD sleep score improved significantly more in the nee- dle embedding and acupuncture groups than in the medication group. HAMD sleep score significantly improved from the first week of treatment in the needle embedding and acupuncture groups. There was a significant difference compared with the medication group （P 〈 0.01 ）. The difference continued to exist at the following 2 and 4 weeks. There was no significant difference among the three groups at 6 weeks. SSRI treatment also improved HAMD sleep score. Conclusion Needle embedding or acupuncture plus SSRIs can signifi- cantly relieve dyssomnia in depression patients. Both produce a quick effect and are superior to simple SSRI treatment. There was no significant difference between needle embedding and acupuncture treatment, but needle embedding therapy decreases treatment fre- quency and has a practical clinical significance.

关 键 词：抑郁症 睡眠障碍 埋针 针刺 SSRI类药物 HAMD量表 

分 类 号：R246.6[医药卫生—针灸推拿学]