补肾纳气方结合西药治疗慢性阻塞性肺疾病临床观察  

Clinical Study of "Decoction of Reinforcing Kidney to Accept Qi" in Treating COPD in Stable Phase

作　　者：倪伟[1] 张惠勇[1] 吴定中[1] 李万义[1] 

机构地区：[1]上海中医药大学附属龙华医院呼吸科,上海200032

出　　处：《上海中医药杂志》2008年第5期15-17,共3页Shanghai Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局基金资助项目(04-05LP21)

摘　　要：目的观察补肾纳气方对稳定期慢性阻塞性肺疾病(COPD)肾不纳气证的临床疗效。方法采用随机单盲研究方法将68例稳定期COPD患者随机分成治疗组和对照组,每组34例。治疗组采用补肾纳气方及常规西药治疗,对照组采用山楂冲剂及常规西药治疗,疗程均为2个月,随访半年。观察两组治疗前后中医证候积分、肺功能、急性发作情况及生活质量。结果治疗组各主要症状积分均较治疗前降低(P<0.05,P<0.01);治疗组中医证候疗效总有效率为64.71%,高于对照组的35.29%(P<0.05);治疗组半年内急性发作次数较治疗前减少,最长持续时间较治疗前缩短(P<0.05,P<0.01);治疗组肺功能指标无明显变化(P>0.05),生活质量显著改善(P<0.05或P<0.01)。结论补肾纳气方可以改善COPD患者症状,降低半年内急性发作次数及最长持续时间,改善患者的生活质量。To observe the effect of ＂Decoction of Reinforcing Kidney to Accept Qi＂ on COPD in stable phase of insufficient kidney not accepting qi. Methods Sixty-eight patients were randomly divided into two groups, 34 cases in each group. Treatment group received ＂Decoction of Reinforcing Kidney to Accept Qi＂ and conventional western medicine therapy for 2 months, and control group were treated with ＂Fruetus Crataegi＂ and western medicine therapy for 2 months. Symptoms, pulmonary function, acute attack, and life quality were obstervsed. Results The total effective rate in treatment group was 64.7%, higher than 35.29% in control group （P〈0.05）. The treatment group had shorter duration and fewer frequency of acute exacerbation in the last 6 months （P〈0.05, P〈0.01）. Pulmonary function in the treatment group had no change after treatment （P〉0.05）, but the quality of life improved （P〈0.05 or P〈0.01）. Conclusion ＂Decoction of Reinforcing Kidney to Accept Qi＂ can improve the clinical symptoms, decrease onset frequency and duration of acute exacerbation in 6 months, promote the quality of life.

关 键 词：慢性阻塞性肺疾病 肾不纳气证 补肾纳气方 临床研究 证候积分 肺功能 生活质量 

分 类 号：R563.9[医药卫生—呼吸系统]