“异丙酚＋芬太尼”在气管拔管术中的应用研究  

Application of Diprivan Combined with Fentanyl in Technique of Airmbe Extubate

作　　者：姜波[1] 陆诚[1] 

机构地区：[1]上海市南汇区中心医院麻醉科,上海201300

出　　处：《麻醉与监护论坛》2008年第2期81-82,共2页Forum of Anesthesia and Monitoring

摘　　要：目的：探讨“异丙酚＋芬太尼”用予气管拨管术减轻拨管对患者呼吸道，循环干扰的临床意义。方法：60例择期腹腔镜胆囊切除的患者随机分成两组，实验组在拔管前给予异丙酚0.5mg／kg，芬太尼0.75μg／kg静注；对照组按常规方法拨管，观察拨管前，吸引。拨管时及拨管后3、5、10分钟的血压，心率。结果：不同处理方法存在组间差别（P〈0.05），患者的收缩压，舒张压，心率在不同的处理方法下不同拔管时相蜜化的趋势不同（P〈0.01），其中实验组不同拨管时相收缩压，舒张压，心率均较为稳定。结论：在拔管期应甩适量异再酚和芬太尼对于呼吸道，心血管反应的抑制殛拨管期血流动力学的平稳有较好的作用。Objective： To investigate clinical significance of relieving intervention of respiratory tract and circulation using diprivan combined with fentanyl in airtube extubate in patients. Methods： Sixty patients in routine laparoscopic cholecystectomy were randomly divided into two groups. Diprivan and fentanyl were respecbvely given with a dose of 0.5mg/kg and 0.75pg/kg before airtube extubate in experimental group. Airtube extubate in control group was used in routine method. Blood pressure and heart rate were observed before extubate, suction, extubate, 3min, 5min, and 10min after extubate. Results： Difference was found between two groups （P〈0.05）. The changed tendency in different phase of extubate was different with systolic blood pressure, diastolic blood pressure and hear rate in different management （P〈0.01）. Systolic blood pressure, diastolic blood pressure and hear rate were comparatively stabile in different phase of extubate in experimental group. Conclusion： It appeared a better effect to inhibit respiratory tract and cardiovascular effects and hemodynamic stabilization with proportionate diprivan and fentanyl during airtube extubate.

关 键 词：异丙酚 芬太尼 拔管木 麻醉 

分 类 号：R541.7[医药卫生—心血管疾病] R169.42[医药卫生—内科学]