大剂量静脉注射免疫球蛋白治疗皮肤粘膜淋巴结综合征  

EFFECT OF INTRAVENOUS HIGH DOSE IMMUNOGLOBULIN ON THE PATIENTS WITH KAWASAKI DISEASE

作　　者：黄旭强[1] 伍曼玲[1] 

机构地区：[1]广州市儿童医院,510120

出　　处：《广东医学》1997年第10期659-661,共3页Guangdong Medical Journal

摘　　要：报告用静脉注射免疫球蛋白治疗皮肤粘膜淋巴结综合征（川崎病）的效果。静注Ig组（17例）临床症状体征缓解迅速，与非静注Ig组（14例）相比，差异有非常显著意义。冠状动脉损害的发生率：前者6.3％，后者35．7％，前者比后者明显降低；冠状动脉损害程度：前者呈轻度扩张，后者发生多发性扩张和动脉瘤.提示：应早期使用大剂量静脉注射免疫球蛋白治疗川崎病，控制急性期炎症过程及预防发生冠状动脉损害.Effect of intravenous high dose immunogloblin (IVIG)on the patients with Kacasaki disease was evaluated. 17cases accepted high dose immunoglobulin and another 14 without as the controf. The treated patients compared with the control was improved in the clinical presentation rapidly.There was significantly higher deference between them.The incidence of damag in coronary arteries in the former (6. 3% ) was markedly lower than in the later (35. 7% ).Most patients treated with IVIG has only mild coronaiyartery dilation, but those without treatment presented the dilation in multiple coronary arteries and aneurysms.The results indicated tha the early intravenous high dose immunoglodulin can control the inflamation of coronary arteries in acute phase and prevent from the damage in coronary arteries in children with Kawasaki disease.

关 键 词：免疫球蛋白 皮肤粘膜淋巴结 综合征 静脉注射 

分 类 号：R597.05[医药卫生—内科学]