小儿定风汤剂治疗小儿原发性癫痫强直-阵挛性发作(痰热挟惊证)30例临床观察  

Clinical Observation on Primary Infantile Tonic-Clonic Epilepsy Manifested as Syndrome of Convulsion due to Phlegm-Heat Treated by Xiaoer Dingfeng Decoction

作　　者：马融[1] 戎萍[1] 魏小维[1] 

机构地区：[1]天津中医药大学第一附属医院儿科

出　　处：《中医杂志》2008年第5期424-427,共4页Journal of Traditional Chinese Medicine

摘　　要：目的观察小儿定风汤剂治疗小儿原发性癫痫强直一阵挛性发作(痰热挟惊证)的有效性和安全性。方法90例患儿随机分为3组,即定风汤剂组、抗痫胶囊组及熄风胶囊组。分别予小儿定风汤剂、抗痫胶囊及熄风胶囊治疗,12个月后观察其发作频率、发作持续时间、脑电图变化,评价其临床疗效及安全性。结果小儿定风汤剂组总有效率达86.67%,优于抗痫胶囊组(P<0.05)。与熄风胶囊组比较差异无统计学意义(P>0.05)。小儿定风汤剂能显著减少癫痫患儿发作频率,缩短发作持续时间,改善脑电图。结论小儿定风汤剂是治疗小儿原发性癫痫强直-阵挛性发作(痰热挟惊证)安全、有效的中药。Objective To observe the effectiveness and salty of Xiaoer Dingfeng Decoction（Decoction to stop wind in children con- vulsion） in the treatment of syndrome of primary infantile convulsion due to phlegm-heat in tonic-clonic epilepsy. Methods Totally 90 infantile patients were randomized into three groups, which were treated by Xiaoer Dingfeng Decoction, Kangxian （Capsule to treat epilepsy） and Xifeng Capsule （Capsule to calm the wind） respectively. Frequency of seizure, lasting duration, and change of electroencephalogram （EEG） were observed 12 months later. Results The total effective rate of Xiaoer Dingfeng Decoction group was 86. 67%, better that that of Kangxian Capsule group（P〈0.05）, no significant difference from that of Xifeng Capsule group （P〉0.05）. It could greatly reduce the frequency of seizure, shorten the lasting duration, and improve the EEG. Conclusion Xiaoer Dingfeng Decoctions is effective and safe for the syndrome of primary infantile convulsion due to phlegm-heat in tonic-clonic epilepsy.

关 键 词：癫痫 强直一阵挛性发作 中医药疗法 小儿定风汤剂 

分 类 号：R272[医药卫生—中医儿科学]