新型水溶性荧光标示剂吲哚方酸菁染料的合成及光谱性能  

Synthesis and Spectral Properties of New Water-soluble Fluorescent Label Squarylium Indocyanine Dyes

作　　者：宋波[1] 张茜[2] 彭孝军[1] 马文辉[1] 王炳帅[1] 付新梅[1] 

机构地区：[1]大连理工大学精细化工国家重点实验室,大连116012 [2]齐齐哈尔大学化学与化学工程学院,齐齐哈尔161006

出　　处：《高等学校化学学报》2008年第5期932-935,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:20376010,20472012)资助

摘　　要：用方酸与不同的N烷基取代吲哚啉季铵盐缩合制备了一系列对称的水溶性方酸菁染料.通过核磁共振氢谱和质谱对合成的染料结构进行了表征,研究了它们在不同溶剂中的吸收和发射光谱.结果表明,随着溶剂极性的增大,染料的吸收光谱发生蓝移,表现为负向溶剂化效应,在极性溶剂中的荧光量子产率比在水中的大.考察了N位取代基对染料水溶液光稳定性的影响,结果表明在吲哚环N原子上引入较大的苄基有助于提高光稳定性,且随着苄基上取代基吸电子能力的增强,染料的光稳定性增强.Six water-soluble squarylium indocyanine dyes were synthesized and their structures were confirmed by ^1H NMR and MS spectroscopy. The absorption and emission spectra of these dyes in water, methanol, ethanol, DMF, DMSO were studied. The spectra of these dyes exhibit a negative solvatochromism. The photo stability of these dyes in water was investigated as well. It is demonstrated that the electron-withdrawing group on N-position of cyanine dyes improves the photo stability as which decreases the photo stability obviously. compared with the dyes with electron-donating group

关 键 词：方酸 菁染料 水溶性 光稳定性 

分 类 号：O626.329[理学—有机化学]