长Q-T间期综合征临床观察  

Clinical observation of long Q-T syndrome

作　　者：杨德彦[1] 陈太波[1] 方全[1] 程康安[1] 高鹏[1] 

机构地区：[1]北京协和医院心内科,100730

出　　处：《心电学杂志》2008年第2期139-141,共3页Journal of Electrocardiology(China)

摘　　要：目的探讨长Q-T间期综合征的临床特点。方法对11例长Q-T间期综合征病例的临床资料进行回顾性分析。结果11例中女性10例,男性1例;先天性5例(首次发病4～27岁),获得性6例(首次发病58～80岁);首发症状9例为晕厥,2例为心悸。6例予补钾治疗,5例予补镁治疗,5例先天性者均接受β受体阻滞剂治疗,其中植入ICD1例,植入起搏器1例。治疗后Q-T/Q-TC间期缩短;有5例晕厥患者随访期间未再发。结论长Q-T间期综合征为心源性晕厥原因之一;先天性患者首次发病年龄较早;补钾、镁为重要治疗措施。先天性患者β受体阻滞剂治疗后仍反复晕厥者应植入ICD。Objective To explore clinical features of long Q-T syndrome（LQTS）. Methods The clinical data of 11 cases （10 females and 1 male） with LQTS were analyzed retrospectively. Results 5 cases had congenital LQTS（age at onset from 4 to 27 years） and 6 had acquired LQTS （age at onset from 58 to 80 years）. 9 cases presented with syncope and 2 with palpitation. 6 cases were treated with potassium and 5 with magnesium. All cases with congenital LQTS were treated with β -adrenergic blockers. Of them, one was treated with implantable cardioverter defribillator（ICD） and I case implanted with pacemaker. Q-T and Q-Tc intervals decreased after therapy. No syncope recurred in 5 cases during follow-up. Conclusion Supplements of potassium and magnesium are important in treatment of LQTS. Age at onset of congenital LQTS is younger. ICD therapy is needed if syncope occurs recurrently after treated with 6 -adrenergic blockers.

关 键 词：长Q—T间期综合征 Q—T间期 晕厥 

分 类 号：R541.7[医药卫生—心血管疾病]