无精子症患者精浆pH值、性激素与生精细胞检测及其意义  

The relation between sexual hormone detection in seminal plasma and spermatogenic cells test in patients with aspermia

作　　者：田英[1] 丁进芳[2] 钟兰君[2] 李芳文[2] 周爱花[2] 侯金霞[1] 

机构地区：[1]兰州大学医学院临床检验学系,兰州73000 [2]甘肃省人民医院临床检验中心

出　　处：《临床泌尿外科杂志》2008年第4期278-279,282,共3页Journal of Clinical Urology

摘　　要：目的：探讨对无精子症患者进行精浆pH值、性激素和生精细胞检测及其意义。方法：对60例无精子症患者根据精液pH值分为高pH值组38例（pH值7.2～8．0），低pH值组22例（pH值≤7．0）；另以20例正常男性作为正常对照组。采用电化学发光免疫法（ECLI）测定精浆性激素水平，用瑞一姬染色法进行精液细胞学检查。结果：高pH值组33例检出生精细胞，精浆中睾酮（T）、卵泡刺激素（FSH）与正常组相比，差异均有统计学意义（P〈0.05）；低pH值组22例均未检出生精细胞，精浆中T、FSH与正常组相比差异均无统计学意义。结论：临床只有对无精症患者精液的pH值、性激素水平与生精细胞学进行综合分析，才能正确诊断发生无精子症的原因，以指导临床治疗。Objective：to detect the sexual hormone in seminal plasma and analyze the spermatogenic cells of the patients with aspermia. Methods：According to the account of PH of seminal plasma, 60 patients of aspermia were divided into high pH group （pH 7.2-8.0） （38 cases） and low pH group （pH〈7.0） （22 cases）. Then 20 normal men were chosen as the control group, electrochemistry luminescence immunity（ ECLI） was used to detect sexual hormone in seminal plasma and Wright-Giemsa stain was used to test the spermatogenic cells in 60 patients with aspermia. Result：In high PH group, spermatogenic cell could be detected in 33 patients. And then there was statistic difference between high PH group and the control group in the follicle stimulating hormone （FSH） and testosterone（T） in seminal plasma （P〈0.05）. spermatogenic cell can not be detected in all 22 in low pH group. There was no statistic difference between low pH group and the control group in the FSH and T in seminal plasma （P〉0. 05）. Conclusion：comprehensive analysis of pH, sexual hormone and spermatogenic cell test in aspermia patients can correctly diagnose the cause of aspermia and have important significance in commanding the clinical treatment

关 键 词：无精子症 性激素 生精细胞 

分 类 号：R698[医药卫生—泌尿科学]