河北省城乡成年居民血脂异常及其危险因素调查分析  

Dyslipidemia and Related Risk Factors Among Adults in Hebei Province

作　　者：栗华[1] 张建新[1] 张中朝[1] 张敬一[1] 朱俊卿[1] 杨雪梅[1] 王玉[1] 

机构地区：[1]河北省疾病预防控制中心慢病防治所,河北石家庄050021

出　　处：《实用预防医学》2008年第2期327-331,共5页Practical Preventive Medicine

基　　金：河北省科学技术研究与发展计划项目资助(06276102D-81)

摘　　要：目的了解河北省成年居民血脂异常现状及其相关危险因素。方法采用多阶段随机抽样,通过问卷、体格测量的方法,调查分析河北20个区（县）4 200名成人血脂异常的流行特征及其相关危险因素。结果河北省成年居民总胆固醇（TC）为4.43 mmol/L、甘油三酯（TG）为1.58 mmol/L,均高于2002年全国平均水平（3.81、1.10 mmol/L）、高密度脂蛋白（HDL-C）为1.30 mmol/L,与全国平均水平相同,低密度脂蛋白（LDL-C）为2.52 mmol/L。该省成年居民总的血脂异常患病率为46.50%（标化率为43.29%）。其中高胆固醇、高甘油三酯、高低密度脂蛋白胆固醇、低高密度脂蛋白胆固醇的患病率分别为：14.68%、30.72%、12.01%、11.29%,标化率分别为：11.02%、26.19%、9.07%、12.51%。该省成年居民的患病率随年龄的增长而升高（χ2=77.71,P〈0.01）,城市为52.38%,高于农村43.98%（χ2=11.71,P〈0.01）。多因素Logistic回归分析显示,年龄组、文化程度、职业、吸烟、超重、向心性肥胖、高血压、高血糖是血脂异常的危险因素（OR值和95%CI分别为1.91,1.49-2.45;1.68,1.06-2.64;1.54,1.03-2.32;1.29,1.06-1.57;1.61,1.36-1.90;1.47,1.11-1.93;1.58,1.37-1.82;1.49,1.21-1.83）。结论河北省成人居民的血脂水平和血脂异常患病率均高于全国平均水平。血脂异常以高胆固醇血症、高甘油三酯血症为主,中老年人群是重点防治人群。Objective To understand the epidemiological status and related risk factors of dyslipidemia among the adults in Hebei Province. Methods A total of 4,200 adults from 20 districts or counties in Hebei Province were selected by multistage stratified random sampling method to conduct questionnaire survey and physical examination. Results The levels of TC, TG, HDL-C and LDL-C were 4.43mmol/L, 1.58mmol/L, 1.30mmol/L, and 2.52mmol/L. The values of TC and TG were higher than the average levels of Chinese reported in 2002. The prevalence rate of dyslipidemia was 46.50% （the age - adjusted rate was 43.29 % ）. The elevated TO, TG, LDL - C and decreased HDL - C accounted for 14.68 %, 30.72 %, 12.01%, and 11.29% respectively; the ageadjusted rates were 11.02%, 26.19%, 9.07%, and 12.51% respectively. The prevalence of diseases was closely related to ageing （x^2 = 77.71, P〈 0.01）. The rate in urban areas （52.38%） was higher than in rural areas （43.98%） （x^2 = 11.71, P〈 0.01 ）. Multiple logistic regression analysis indicated that agegroup, educational level, occupation, smoking, overweight, central obesity, hypertension, and hyperglycemia were the major risk factors of dyslipidemia （OR values and 95% CI equaled 1.91, 1.49-2.45; 1.68, 1.06-2.64; 1.54, 1.03-2.32; 1.29, 1.06-1.57; 1.61, 1.36-1.90; 1.47, 1.11-1.93; 1.58, 1.37-1.82; 1.49, 1.21-1.83）. Conclusions The levels of serum lipids and the prevalence rate of dyslipidemia among the adults in Hebei Province are higher than the average levels in China. The most common dyslipidemia are elevated TC and TG, and the middle - aged and senile people are the key target population.

关 键 词：成年居民 血脂异常 危险因素 调查分析 

分 类 号：R589.2[医药卫生—内分泌]