河北某县农村人群甲肝病毒抗体阳性率调查  

Detection of HAV Antibody Levels of Rural Population in a County of Hebei Province

作　　者：田茶[1] 刘怀风 张志勇[3] 郝志勇[3] 张新江[3] 褚娟[3] 李军[1] 马景臣[1] 陈吉朝[3] 齐顺祥[1] 张勇[4] 

机构地区：[1]河北省疾病预防控制中心,河北石家庄050021 [2]正定县中医院 [3]正定县疾病预防控制中心 [4]中国疾病预防控制中心病毒病预防控制所

出　　处：《实用预防医学》2008年第2期426-427,共2页Practical Preventive Medicine

摘　　要：目的了解疫苗时代农村人群甲肝病毒抗体水平。方法采取整群分层抽样方法对河北正定县某乡八个自然村共18 149人采血9 825人份,用ELISA方法进行血清抗-HAV IgG检测,用Epi-info软件分析处理。结果人群抗-HAV阳性率平均为88.37%,甲肝易感者的年龄明显后移,1-20岁人群抗-HAV阳性率呈波浪形上升,20岁以后抗体阳性率达90%以上,并稳定在高水平。结论在高抗体阳性率屏障下,甲肝病例多呈散在发生,不易出现流行。Objective To understand the anti HAV antibody levels among rural population in vaccination era. Methods A total of 9,825 serum specimens were collected from 18,149 individuals in 8 villages of Zhengding County for anti - HAV IgG assay by ELISA, the testing data were analyzed by Epi info software. Results The average anti - HAV positive rate was 88.37 %. The age of susceptible population moved backward significantly. The anti - HAV positive rate of population increased among the age group of 1 -20 years and reached 90 % after 20 years old. Conclusions Under the high level of anti- HAV, the occurrence of symptomatic HAV infection happened sporadically, and the epidemic would happen rarely.

关 键 词：抗-HAV IGG 横断面调查 农村 

分 类 号：R373.21[医药卫生—病原生物学]