3-硝基吡唑及其盐类的合成与表征  

Synethsis and Characterization of 3-Nitropyrazole and its Salts

作　　者：李洪丽[1] 熊彬[1] 姜俊[1] 郑晓东[1] 李智鹏[1] 马玉霞[1] 

机构地区：[1]西安近代化学研究所,陕西西安710065

出　　处：《火炸药学报》2008年第2期102-104,108,共4页Chinese Journal of Explosives & Propellants

摘　　要：为合成3-硝基吡唑盐,以吡唑为原料,经HNO3-Ac2O-HAc三元硝化体系首先制得N-硝基吡唑,然后经高温重排转化为3-硝基吡唑,3-硝基吡唑与无机铅盐和铜盐反应生成有机铅盐和铜盐。用熔点、IR、NMR及元素分析等表征和确定了目标化合物的结构。通过优化各步反应条件,提高了反应的收率:硝化收率为85.5%,重排收率为92.8%,总收率达到79.3%。In order to synthesize the salts of 3-nitropyrazole,N-nitropyrazole was synthesized with pyrazole as raw material, and HNO3-Ac20-HAc system as nitration agent. N-nitropyrazole at high temperature was rearranged as 3-nitropyrazole. Its organic copper and lead salts were synthesized by the reaction of 3-nitropyrazole with some inorganic copper and lead salts. The structure of products were characterized by mehing point, IR, NMR and elemental analysis, showing that the products were target products. The optimum reaction yield were 85.5% for nitration, 92.8% for rearrangement reaction and 79.3% for total yield.

关 键 词：有机合成 吡唑 N-硝基吡唑 3-硝基吡唑 硝化 重排 

分 类 号：TQ252.1[化学工程—有机化工]