儿童注意缺陷多动障碍中枢神经递质的对照研究  

Comparison study of neurotransmitters of attention deficit hyperactivity disorder in the children

作　　者：熊忠贵[1] 金涛[1] 徐海青[1] 石淑华[2] 

机构地区：[1]湖北省妇幼保健院,武汉430070 [2]华中科技大学同济医学院

出　　处：《中国妇幼保健》2008年第16期2229-2231,共3页Maternal and Child Health Care of China

基　　金：湖北省卫生厅青年科技人才基金资助项目(QJX2005-12)

摘　　要：目的:分析儿童注意缺陷多动障碍(ADHD)血清多巴胺、去甲肾上腺素水平,为开展儿童ADHD的防治工作提供科学依据。方法:采用多巴胺、去甲肾上腺素试剂盒,运用ELISA方法分析儿童ADHD血清多巴胺、去甲肾上腺素水平。结果:病例组血清多巴胺和去甲肾上腺素水平分别为(1.42±0.34)ng/ml和(177.70±37.92)pg/ml,对照组血清多巴胺和去甲肾上腺素水平分别为(1.94±0.42)ng/ml和(206.20±42.45)pg/ml;与对照组比较,儿童ADHD血清多巴胺、去甲肾上腺素水平均具有显著性差异(P<0.05)。结论:中枢神经递质在儿童ADHD的发病中可能起到一定的作用。Objective： To analyze serum levels of dopamine and noradrenalin of children with attention deficit hyperactivity disorder （ADHD） . Methods： ELISA was applied to analyze serum levels of dopamine and noradrenalin of children with ADHD using dopamine and noradrenalin kits. Results： The serum levels of dopamine and noradrenalin of case group were 1.42 - 0. 34 ng/ml and 177. 70 - 37.92 pg/ml, those of control group were 1, 94 - 0. 42 ng/ml and 206.20 - 42.45 pg/ml accordingly. The serum levels of dopamine and noradrenalin had significantly difference between ease and control groups （P〈0. 05） . Conclusion： The the incidence of children with ADHD. play an important role in

关 键 词：儿童 ADHD 中枢神经递质 

分 类 号：R179[医药卫生—妇幼卫生保健]