湖州市甲型、戊型病毒性肝炎及其重叠感染的家庭分布研究  

Research on Familial Aggregation and Superinfection of Hepatitis A and Hepatitis E in Huzhou City

作　　者：沈建勇[1] 韩建康[1] 金玫华[1] 姚文庭[1] 邹勇[1] 

机构地区：[1]湖州市疾病预防控制中心,浙江313000

出　　处：《中国预防医学杂志》2008年第5期355-357,共3页Chinese Preventive Medicine

基　　金：湖州市社会发展科研支持项目(2006YS15)

摘　　要：目的分析甲肝、戊肝及其重叠感染的家庭聚集性现象。方法在湖州市自然人群中采用多阶段分层整群随机抽样方法抽取682户家庭,共计1666人作为研究对象,用酶联免疫吸附(ELISA)方法测定其血清HAV-IgG、HEV-IgG,并用二项分布齐性检验的G统计量法,进行家庭聚集性分析。结果甲肝、戊肝及其重叠感染率分别为61.10%、44.96%和32.23%,其中戊肝及甲、戊肝重叠感染具有明显的家庭聚集性。结论湖州属甲肝、戊肝的高流行区,在制定防控措施及健教方案时,应特别注意家庭的单元性和重视发挥家庭单元的特殊作用。Objective To analyse familial aggregation of Hepatitis A , Hepatitis E and the superinfection of them. Methods A total of 1 666 people were selected from 682 families in Huzhou city by the method of multi - stage stratified cluster random sampling. Blood samples were collected from the participants and the serum HAV - IgG, HEV - IgG were tested by using ELISA. The data were analyzed with G test of homogeneous in statistical binomial distribution. Results The total infection rates of HAV, HEV and the superinfection rate of them were 61.10%, 44. 96% and 32.23%, respectively. Evidences for familial aggregation of Hepatitis E and the superinfection of Hepatitis A and E were found. Conclusion Huzhou city is a high prevalence area of Hepatitis A and E. Familial aggregation should be emphasized in proposing control measures and developing health education programs.

关 键 词：病毒性肝炎 甲型 戊型 重叠感染 家庭聚集性 C统计量 防制措施 

分 类 号：R512.6[医药卫生—内科学]