抗焦虑抑郁药对伴焦虑抑郁障碍高血压的疗效观察  

EFFECT OF ANTI-ANXIETY DRUGS AND ANTIDEPRESSANTS ON PATIENTS WITH ESSENTIAL HYPERTENSION COMBINED ANXIETY AND DEPRESSION

作　　者：林楚卿[1] 赖怀远[1] 刘满芬[1] 

机构地区：[1]广东省汕头市第四人民医院,515021

出　　处：《中国煤炭工业医学杂志》2008年第5期626-627,共2页Chinese Journal of Coal Industry Medicine

摘　　要：目的探讨抗焦虑抑郁药物治疗对伴发焦虑抑郁的高血压患者的治疗效果及其临床意义。方法对55例高血压患者进行焦虑自评量表(SAS)、抑郁自评量表(SDS)评分,将评分阳性者随机分为实验组(常规治疗+黛力新:氟哌噻吨0.5mg+美利曲辛10mg)及对照组(仅用常规治疗),并随访8周;比较二组血压的降幅度以及治病前后SAS、SDS得分。结果治疗后实验组较对照组的血压下降幅度大;SAS、SDS评分较治疗前明显下降,对照组有轻度下降但仍明显高于常模。结论抗焦虑抑郁药物(黛力新)协同治疗伴焦虑抑郁障碍的高血压患者疗效显著,可以缩短降血压显效时间,同时显著降低高血压患者的焦虑、抑郁和躯体症状的水平。Objective To investigate the effect of deanxit on subjects with essential hypertension combined anxiety and depression and to explore its clinical implications. Methods After 55 cases being evaluated with essential hypertension by SAS and SDS, the positive subjects were followed up for 8 weeks. According to baseline assessments, the subjects were randomly divided into experimental group （routine treatment and Deanxit） and control group （only routine treat- ment）. The reduction of mean blood pressure and score of SAS and SDS were compared. Results Compared with control group, the reduction of mean blood pressure was much great, the scores of SAS and SDS in experiment groups were significantly lower than those before treatment while little changes in the scores of SAS and SDS was found in those of the control group. Conclusion Significantly synergic effect of the anti-anxiety drugs and antidepressants combined an- ti- hypertension drugs on anxiety and depression in patients with hypertension was found. The anti- anxiety and anti-depressant treatment could increase efficiency rate, reduce degree of anxiety, depression and somatic symptoms in tients with essential hypertension.

关 键 词：高血压 焦虑 抑郁 黛力新 

分 类 号：R595.5[医药卫生—内科学] R544.1[医药卫生—临床医学]