尘螨变应原皮肤点刺试验与血清特异性IgE的相关性研究  

Association between skin prick test of dust mites and serum specific IgE

作　　者：王向东[1] 张罗[1,2] 赵岩[1] 刘朔[1] 顾瑛[1] 韩德民[1,2] 

机构地区：[1]首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,耳鼻咽喉头颈科学教育部重点实验室(首都医科大学),北京100730 [2]北京市耳鼻咽喉科研究所

出　　处：《中国耳鼻咽喉头颈外科》2008年第5期249-251,共3页Chinese Archives of Otolaryngology-Head and Neck Surgery

基　　金："十一五"国家科技支撑计划资助项目(2007BAI18B15);北京市科委科技计划项目(Z0005190041531);北京市科技新星计划(2006A67)联合资助

摘　　要：目的探讨尘螨变应原皮肤点刺试验(skin prick test,SPT)结果与血清特异性IgE(specific IgE,S-IgE)检测值之间的相关性。方法分析170例接受尘螨变应原SPT和相应的血清S-IgE检测的变应性鼻炎患者不同皮肤风团直径和不同皮肤反应指数(skin index,SI)对应的血清S-IgE的差异。结果尘螨变应原SPT不同皮肤风团直径和不同SI对应的血清S-IgE存在显著性差异,随着皮肤风团直径或SI的增加,血清S-IgE阳性率和级别也显著增加。结论尘螨变应原SPT结果和血清S-IgE结果存在相关性。OBJECTIVE To evaluate the association between the results of skin prick test （SPT） of dust mites and serum specific IgE （S-IgE）. METHODS A total of 170 patients with allergic rhinitis received SPT and detection of S-IgE of Der p and Der f. The positive rates and grades of S-IgE to different diameters of skin reaction or skin index （SI） were compared. RESULTS The positive rates and grades of S-IgE showed significant differences among different diameters of skin reaction or skin index （SI） patients. The positive rates and grades of S-IgE increased significantly according to the diameters of skin reaction or SI. CONCLUSION There is a significant association between SPT of dust mites and S-IgE.

关 键 词：鼻炎 变应性 常年性 尘螨科 皮肤试验 免疫球蛋白E 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]