藏鸡心脏高海拔低氧适应相关酶的研究  

CARDIAC ENZYMES RELATED TO HIGH-ALTITUDE HYPOXIC ADAPTATION IN TIBETAN CHICKEN

作　　者：张浩[1] 吴常信[1] 强巴央宗[2] 凌遥[1] 唐晓惠[2] 

机构地区：[1]中国农业大学动物科技学院,北京100094 [2]西藏农牧学院畜牧兽医系,西藏林芝860000

出　　处：《中国应用生理学杂志》2008年第2期233-236,共4页Chinese Journal of Applied Physiology

基　　金：教育部科学技术重大项目(10404);博士后科学基金项目(2005038098)

摘　　要：目的:研究藏鸡心脏对高海拔低氧适应性的生理特征。方法:本研究将藏鸡、矮小隐性白和寿光鸡分别饲养在低海拔和高海拔环境,测定10周龄时心脏重量、心肌乳酸(LA)和乳酸脱氢酶(LDH)、琥珀酸脱氢酶(SDH)活性。结果:结果显示藏鸡在高海拔环境中,心脏相对重量未明显增加,心肌LA低于对照鸡,LDH与对照鸡差异不显著,而SDH活性明显高于对照鸡。结论:结果说明了藏鸡对高海拔低氧环境的适应,不是通过增加心脏器官的重量,也不是通过提高无氧代谢的水平,较高的SDH活力对藏鸡心肌低氧适应有一定的意义。SDH是藏鸡适应低氧的一种标志酶。Aim： The purpose of this experiment was to investigate the cardiac physiological characteristics for adaptation to high-altitude hypoxia in chickens. Methods： Tibetan, Dwarf Recessive White and Shouguang chickens were fed at low-and high-altitude, and measurements were made in heart weights, lactic acid （LA）, lactate dehydrogenase （LDH）, and succinate dehydrogenase （SDH） at the age of 10 weeks. Results： The results showed that Tibetan chickens at high-altitude had lower heart weight and LA content, and similar LDH activity, and higher SDH activity when compared to Dwarf Recessive White and Sbouguang chickens.Conolusion： It was concluded that the cardiac mechanisms of high-ahitude hypoxic adaptation in Tibetan chickens were increasing neither heart weight, nor level of anaerobic metabolism, but the higher SDH activity was significant to the adaptation. The SDH was a symbol enzyme for hypoxic adaptation in Tibetan chicken.

关 键 词：藏鸡 海拔 低氧适应 心脏 

分 类 号：R811.2[医药卫生—放射医学]