超声对绵羊红细胞渗透脆性实验的影响  

Effects of Ultrasound on Osmotic Fragility Test of Sheep Red Blood Cells

作　　者：于廷和[1] 赵卫华[1] 超纯亮 李岱容[1] 蔡汉钟[1] 王智彪[1] 

机构地区：[1]重庆医科大学医学超声工程研究所,630046

出　　处：《中国超声医学杂志》1997年第12期1-3,共3页Chinese Journal of Ultrasound in Medicine

基　　金：国家"九五"重点攻关项目

摘　　要：绵羊红细胞受不同剂量超声辐照，根据剂量一效应曲线求出不致细胞急性损伤之超卢剂量．观察受此种剂量辐照之红细胞与对照组红细胞渗透脆性实验差异。结果发现：25．6W／cm2×1I2和32·4W／cm2×5s为不致红细胞破坏之最大剂量，经此二种刺量处理之红细胞渗透脆性增加（P／0．01），25．6W／cm2×10s组细胞膜脆件增加大于32．4W／cm2×5s组（P＜O．005）。提示亚致死置超卢辐照可致细胞膜通透性增加。Sheep red blood cells were irradiated by ultrasound with dosage series. cell vitality measured and the dosages that didn' t lead to acute cell damage were tetermined. The membrane permeability reflected by osmotic fragility was tested. The results were: (1) 25. 6W/cm2 × 10s and 32. 4W/cm2 × 5s didn' t lead cell killing immediately, (2) the membrane fragility increared in cells irradiated by 25. 6W/cm2 × 10s or 32. 4W/cm2 × 5s, as compared with the control (P<0. 01 ), (3) the fragility of membrane increased more in group of 25. 6W/cm2 × 10s than in group of 32. 4W/cm2 × 5s (P<0. 005), These indicated that sublethal ultrasound dosage could promote membrane permeability.

关 键 词：红细胞 渗透脆性 超声波诊断 

分 类 号：R331.141[医药卫生—人体生理学]