定量CT椎体骨密度测定诊断骨质疏松症(英文)  

Diagnosis of osteoporosis by vertebral bone mineral density measurement with quantitative computed tomography

作　　者：沈宁江[1] 李一波[1] 陈文清[2] 刘光洪[2] 

机构地区：[1]海南省人民医院骨病外科,中国海口570311 [2]海南省人民医院CT室,中国海口570311

出　　处：《中国矫形外科杂志》2008年第11期826-828,共3页Orthopedic Journal of China

摘　　要：[目的]探讨定量CT(QCT)椎体骨密度(BMD)测定在诊断骨质疏松症中的临床价值和诊断标准。[方法]对53例健康无症状中老年人和68例临床拟诊骨质疏松患者进行L1～4椎体BMD测定。[结果]健康中老年人BMD随年龄增长而明显降低,有显著性差异。以BMD≤x-2.0SD为诊断骨质量疏松症标准有68例,且各年龄段的BMD值均明显低于骨量截断值;如以BMD≤x-2.5SD为诊断标准则有60例。[结论]QCT诊断骨质疏松症敏感、准确、重复性强,易于推广应用。以BMD≤x-2.0SD为诊断标准,更符合临床实际病例,并能减少漏诊。[ Objective] To evaluate the clinical value of diagnosing osteoporosis with vertebra bone mineral density （BMD） by measurement with quantitative computed tomography （QCT） . [ Method] BMD in of lumbar vertebrae （L1-4 ） were measured by QCT in 53 healthy middleaged persons or elderly persons （ group A） and 68 osteoporosis patients （ group B） . [ Result] BMD in group A declined obviously as age increasing with significant differences （ P 〈 0. 01 ） . In group B, all 68 patients showed osteoporosis according to the diagnostic standard of BMD ≤x-2. 0SD. Sixty patients showed osteoporosis if the diagnostic standard was set to BMD ≤x-2. 5SD. The BMD values of different age group was lower than the bone quantity block values. [ Conclusion] As a method for diagnosing osteoporosis, QCT has advantages of high sensitation, being precise, being reproducible and is easy for applying. It would be more practical and could decrease mis - diagnosing if the diagnostic standard was BMD≤x-2.0SD.

关 键 词：定量CT 骨质疏松 骨密度测定 

分 类 号：R580[医药卫生—内分泌]