无肛畸形胎鼠盆底横纹肌复合体m-ATPase组织化学研究  

The m-ATPase Histochemical Study of Striomuscular Complex in Murine Fetus with Anorectal Malformation

作　　者：张志波[1] 王练英[1] 李正[1] 

机构地区：[1]中国医科大学第二临床学院小儿外科,沈阳110003

出　　处：《中华小儿外科杂志》1997年第6期354-356,共3页Chinese Journal of Pediatric Surgery

基　　金：国家自然科学基金(NO39370696)

摘　　要：目的:为了解无肛畸形胎鼠盆底横纹肌复合体的组织化学特征。方法:对39只无肛畸形胎鼠(高位8只、中位10只、低位21只)盆底横纹肌复合体进行 ATP 酶染色,光镜下观察单位面积内肌纤维数及Ⅰ、Ⅱ型肌纤维所占比例。结果:中、高位无肛畸形单位面积肌纤维数和Ⅰ型肌纤维所占比例较正常鼠明显减少(P<0.001),而低位无肛则与正常鼠近似。结论:横纹肌复合体肌纤维组化类型异常也是无肛畸形的一种病理改变。Objective:To study the histochemical characteristics of striomuscular complex in murine fetus with anorectal malformation.Methods:The striomuscular complex of pelvic floor of 39 murine fetus(high 8,intermediate 10,low 21)were stained with ATPase and observed under microscope.The total of muscular fiber per unit area and the percentage of type Ⅰ and Ⅱ fibers were calculated.Results:The total of muscular fibers and percentage of type Ⅰ fibers in the high and intermediate type was lower than that in the normal mice group,while in the low type the to- tal was almost equal to that of the normal.Conclusions:The histochemical abnormality of stri- omuscular complex of the pelvic floor is one of the pathologic changes in anorectal malformations.

关 键 词：无肛畸形 横纹肌复合体 ATP 酶 组织化学 

分 类 号：R714.431[医药卫生—妇产科学]