大环内酯类抗生素-阿奇霉素在疟疾预防和治疗中的应用  

The application of azithromycin,a macrolides antibiotics in prevention and treatment of malaria

作　　者：贺颖[1] 黄亚铭[1] 

机构地区：[1]广西医科大学,广西南宁530021

出　　处：《中国病原生物学杂志》2008年第5期394-395,399,共3页Journal of Pathogen Biology

摘　　要：阿奇霉素是近几年开发生产的第2代大环内酯类抗生素,体外试验和动物试验及在现场疟疾病人治疗观察结果表明,单服该药对抗性株和敏感株疟疾感染均具有治疗和预防作用,与其他抗疟药物配伍使用效果更佳。Azithromycin, a recently developed clinical antibiotic, belongs to the second generation of macrolides antibiotics. The investigation is done in vitro and in vivo of animal and human models shows that the azithromycin alone can treat and prevent sensitive and resistant strains of malaria, and has better effect if it is combined with other antimalaria drugs.

关 键 词：大环内酯类抗菌素 阿奇霉素 疟疾 预防和治疗 综述 

分 类 号：R978.15[医药卫生—药品] R531.3[医药卫生—药学]