38例住院患儿维生素K营养状况分析  

Analysis of the Nutrition Status of Vitamin K on 38 Cases of Hospitalized Children

作　　者：周金平[1] 戴玉良[1] 王小革[1] 杨振朋[1] 张会丰[2] 

机构地区：[1]唐山市人民医院儿科,唐山063001 [2]河北医科大学第二医院儿科

出　　处：《中华妇幼临床医学杂志（电子版）》2008年第3期25-26,共2页Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)

基　　金：唐山市卫生局科研立项项目(04134621C)~~

摘　　要：目的了解住院儿童维生素K的营养状况。方法ELISA法测定2005年10月至2005年12月在唐山市人民医院的38例儿科住院患儿的血浆凝血酶原前体蛋白(protein induced by vitamin K absence or antagonists-Ⅱ,PIVKA-Ⅱ)含量(正常值<2ng/ml)。结果本组38例因感染性疾病住院的4个月至12岁患儿中,血浆凝血酶原前体蛋白含量≥2ng/ml为16例,阳性率为42.11%。本研究显示患儿年龄与血浆凝血酶原前体蛋白含量无相关性(r=-0.2369,P=0.1521);病程(d)与血浆凝血酶原前体蛋白含量无相关性(r=-0.2676,P=0.1043)。结论本组大部分住院患儿存在亚临床维生素K缺乏,应引起高度重视。Objective To investigate the nutrition status of vitamin K on hospitalized children. Methods There were 38 cases of children hospitalized in the department of pediatrics for infective disease, the People＇s Hospital of Tangshan （from October 2005 to December 2005）, whose concentrations on protein induced by vitamin K absence or antagonists-Ⅱ（PIVKA-Ⅱ ） in plasma were determined and quantified by enzyme linked immunoassay （normal value〈2 ng/ml）. Results 16 cases were positive in protein induced by vitamin K absence or antagonists- Ⅱ in 38 children （4 months to 12 years old）. The positive ratio was 42.11%. Protein induced by vitamin K absence or antagonists- Ⅱ concentration in plasma had no correlation with children＇s ages （r = - 0.2369, P = 0.1521 ）, protein induced by vitamin K absence or antagonists Ⅱ concentration in plasma had no correlation with days of having ill （r=-0. 2676,P= 0. 1043）. Conclusion A majority of hospitalized children with vitamin K subclinical absence should be paid attention to.

关 键 词：维生素K 凝血酶原前体蛋白 儿童 

分 类 号：R723[医药卫生—儿科]