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机构地区:[1]湖北中医学院医学检验与技术系,湖北武汉430065 [2]湖北省中医院检验科,湖北武汉430061
出 处:《湖北中医学院学报》2008年第1期10-12,共3页Journal of Hubei College of Traditional Chinese Medicine
摘 要:目的比较心肌肌钙蛋白-I(cTnI)、肌酸激酶同工酶MB质量(CK-MB mass)对急性心肌梗死(AMI)的诊断价值。方法采用美国Beckman Coulter仪器公司Access型全自动免疫系统、微粒子化学发光法在不同时间定量测定58例急性心肌梗塞患者(AMI组)和50例健康体检者(对照组)血浆中cTnI浓度和CK-MB质量。结果AMI组血浆cTnI浓度和CK-MB质量高于对照组(P〈0.01),cTnI出现时间(3-6h)早于CK-MB质量(3-8h),达峰时间(18-24h)晚且短于CK-MB质量(9-36h),恢复时间(7-18d)晚且长于CK-MB质量(2-4d)。结论cTnI和CK-MB质量对AMI的诊断时间和疗效评价时间存在差异,故联合检测对AMI的早期诊断具有更宽的诊断时间窗,能更准确地诊断AMI。Objective: To compare with the diagnosis value of cardiac troponin I (cTnI) and creatine kinase - MB mass (CK - MB mass) on acute myocardial infarction (AMI) Method: Serum of 58 AMI patients (AMI group) and 50 healthy people (control group) are examined for concentrations of cTnI and CK - MB mass, by Access Immunoassay System of Beckman Coulter. Results: The cTnI and CK -MB mass serum concentration of AMI group are higher than control group (P 〈0. 01 ) . The appearace time of cTnI (3 -6h) is earlier than CK - MB mass (3 - 8h). The peak time of cTnI ( 18 -24h) is later and shorter than CK - MB mass (9 - 36h). The recovery time of cTnI (7 - 18d) is later and longer than CK - MB mass (2 - 4d) Conclusions: cTnI and CK - MB mass diagnosis time and evaluation time on AMI are different. The combined detection of both has a boarder diagnosis time window and could make a more accurate diagnosis of AMI.
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