^20lTl定量门控心肌灌注体层显像与^99mTc-红细胞门控心血池显像测定左心室射血分数的对比研究  

Comparison study of left ventricular ejection fraction measured by ^20lTl gated myocardial imaging and ^99mTc-red blood cell gated blood-pool imaging

作　　者：袁建伟[1] 冯彦林[1] 贺小红[1] 余丰文[1] 刘德军[1] 温广华[1] 黄克敏[1] 

机构地区：[1]广东省佛山市第一人民医院核医学科,528000

出　　处：《国际放射医学核医学杂志》2008年第2期86-88,共3页International Journal of Radiation Medicine and Nuclear Medicine

摘　　要：目的探讨^20lTl定量门控心肌灌注体层显像与^99mTc-红细胞门控心血池显像测量左心室射血分数（LVEF）的相关性。方法72例受检者接受^20lTl静息门控心肌灌注体层显像，用AUTOQUANT 4．21软件测量LVEF，并与24h内的静息^99mTc-红细胞平衡法门控心血池显像结果进行比较。结果①门控心肌灌注体层显像与门控心血池显像测量LVEF值的结果呈明显正相关（r=0．554，P=0．000），两种方法无统计学差别（t=1．194，P〉0．05）。②不同疾病组之间两种测量方法无统计学差异（P值均大于0．05）。③门控心肌灌注体层显像及门控心血池显像测量的LVEF值分别为（64．68±10．77）％和（62．46±8．99）％，门控心肌灌注体层显像测量的LVEF值要比门控心血池显像高出3．55％。结论^20lTl控心肌灌注体层显像与^99mTc-红细胞门控心血池显像测量LVEF值的相关性好且结果准确，但门控心肌灌注体层显像的LVEF测量值要稍高于门控心血池显像。Objective To explore the correlation of automatic quantification of left ventricular ejection fraction （LVEF） from gated myocardial perfusion SPECT with ^20lTl and rest equilibrium gated blood-pool imaging with ^99mTc-red blood cell. Methods Rest gated myocardial perfusion SPECT with ^20lTl was performed on 72 cases. AUTOQUANT 4.21 software was used to measure LVEF. Rest equilibrium gated blood-pool imaging was also performed within 24 h. The values of LVEF measured by two methods were calculated and compared. Results ①There were strong correlation between the LVEF measured by rest gated myocardial perfusion SPECT and rest equilibrium gated blood-pool imaging（r=0.554, P=O.O00）. There was no significant difference between the two methods （t =1.194, P〉0.05）. ②There was no significant difference between the two methods among different disease groups. ③The values of LVEF measured by two methods were （64.68 ±10.77 ）% and （62.46±8.99）%. The values of LVEF measured by gated myocardial perfusion SPECT was higher 3.55% than rest equilibrium gated blood-pool imaging. Conclusion There was good correlation between the LVEF measured with gated myocardial perfusion SPECT by AUTOQUANT 4.21 software and gated blood-pool imaging. The LVEF can be accurately evaluated using gated myocardial perfusion SPECT with ^20lTl. The value of LVEF measured by gated myocardial perfusion SPECT was higher than rest equilibrium gated blood-pool imaging.

关 键 词：门控血池显像 门控心肌灌注显像 铊放射性同位素 体层摄影术 发射型计算机 单光子 

分 类 号：R817.4[医药卫生—影像医学与核医学]