糖皮质激素联合阿昔洛韦治疗老年带状疱疹临床疗效观察  

Clinical Effect Investigation of Herpes Zoster with Glucocortiocoid and Acyclovir in Old Patients

作　　者：周静[1] 

机构地区：[1]四川省科学城医院皮肤科,四川绵阳621900

出　　处：《川北医学院学报》2008年第3期255-256,共2页Journal of North Sichuan Medical College

摘　　要：目的探讨糖皮质激素(GC)联合阿昔洛韦治疗老年带状疱疹的疗效、安全性。方法随机分为治疗组和对照组,治疗组:30例,糖皮质激素联合阿昔洛韦应用。对照组:30例,单用阿昔洛韦,其余治疗方法相同,疗程均为15-20天,随访8周。结果两组在缓解和消除带状疱疹神经痛方面有统计学差异(p<0.01),在皮损结痂消褪时间上无统计学差异(p>0.05)。结论早期联合应用糖皮质激素(GC)和阿昔洛韦治疗带状疱疹是有效的。Objective To investigate the curative effect and safety of applying glucocorticoid（GC） and acyclovir to patients with acute herpes zoster. Methods Patients were divided randomly into two groups. Thirty cases in the treatment group were treated with glucocorticoid and acyclovir, and the other thirty cases in the control group were treated with acyclovir alone, both for 15 -20 days. All patients were followed up for 8 weeks after the end of treatment. Results There was a significant difference between the two groups with respect to the time to first relief of pain, and time to complete relief of pain（p 〈 0.01 ） . There was no significant differences between the two groups with respect to the time to first loss of crusts （p 〉 0.05 ）. Conclusions Early use of glucocorticoid in combination with acyclovir was effective in treating older patients.

关 键 词：带状疱疹 糖皮质激素 治疗 神经痛 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]