几种β-二酮化合物的合成及表征  

Synthesis and Characterization of Three β-diketones

作　　者：刘兴旺[1,2] 王娜[1] 索全伶[1] 卢尚功[1] 

机构地区：[1]内蒙古工业大学化工学院,呼和浩特010051 [2]包头师范学院化学学院,内蒙古包头14030

出　　处：《内蒙古大学学报（自然科学版）》2008年第3期281-283,共3页Journal of Inner Mongolia University：Natural Science Edition

基　　金：内蒙古自然科学基金资助项目(200508010210)

摘　　要：在三苯基膦二氯化钯/碘化亚铜的催化下,对溴苯甲酸甲酯与苯乙炔发生偶合反应,生成化合物1,化合物1分别与苯乙酮、2-乙酰呋喃、2-乙酰噻吩发生克莱森缩合反应,合成了三种新型β-二酮化合物3(a-c),并利用1HNMR,IR,MS,元素分析对其结构进行了表征.The synthesis of three novel β-diketones is described. Compound 1 was formed by coupling reaction of methyl p-bromobenzoate with phenylacetylene in the presence of Triphenyl phosphate-palladium chloricle/Cuprous iodide as catalyst in solvent triethylamine. Compound 1 reacts with acetophehone,2-acetyifuran and 2-acetylthiophene respectively under the conditions of Claisen condensation to afford the correspond β-diketones 3 （a-c） with good yield. The products were characterized by element analysis and the spectra data of IR and ^1HNMR.

关 键 词：Β-二酮 偶合反应 克莱森缩合 

分 类 号：O621.32[理学—有机化学]