体外静脉-静脉转流下原位肝移植围术期的动脉血酸碱和生化变化  

THE ACID-BASE AND BIOCHEMICAL CHANGES IN CLINICAL ORTHOTOPTIC LIVER TRANSPLANTATION WITH VENO-VENOUS BYPASS

作　　者：邓天忠[1] 陈秉学[1] 黑子清[1] 

机构地区：[1]中山医科大学附属第一医院麻醉科,510080

出　　处：《广东医学》1997年第12期795-796,共2页Guangdong Medical Journal

摘　　要：对6例行原位肝移植术患者，在无肝期采用左侧股静脉和门静脉至左侧腋静脉的体外静脉－静脉转流，转流量为400～800ml／min。围术期分别在转流前、转流期30分钟和60分钟、开放后新肝期30分钟、术毕等采动脉血作酸碱和生化检查。结果显示：BE在转流60分钟有所下降（P＜O．05），Ca2＋在开放后30分钟显著下降（P＜0．05），其它指标如pH、K＋等变化无显著差异（P＞0．05）。表明在体外静脉－静脉转流下进行肝移植，避免了无肝期和开放期血液酸碱和生化的急剧变化，能减少或避免围术期代谢性酸中毒和高钾血症。Six patients received orthotoptic liver transplantation.Veno-venous bypass was performed in enheptic phase. The rate of rotation 400～800ml/min. The profiles of acid and biochemical changes in perioperation were obtained. The results showed:BE slight decreased in 60 minutes on bypass(P <0. O5 ); the serum Ca2 + decreased greatly after the hep-tic revascularization (P < O.O5. pH and serum K+ and or sohad no changes (P > 0.05 ). It was concluded that the clinical orthotoptic liver transplantation under veno-venous bypass could avoid greatly acid- base and biochemical changes the group of heptic transplantation avoided obvious metabolic aci-dosis and hyperkalemia.

关 键 词：酸碱代谢 血生化 静脉转流 肝移植 

分 类 号：R657.3[医药卫生—外科学]