三维大血管增强磁共振血管造影技术及其临床应用价值探讨  

The Value of Clinical Applications of Three-dimensional Dynamic Contrast-enhanced MR Angiography in Large Vessels Diseases

作　　者：谢道海[1] 郭亮[1] 郭茂凤[1] 傅引弟[1] 陈剑华[1] 

机构地区：[1]苏州大学附属第一医院放射科,江苏苏州215006

出　　处：《苏州大学学报（医学版）》2008年第2期271-273,共3页Suzhou University Journal of Medical Science

摘　　要：目的探讨三维增强磁共振血管造影(3D CE MRA)的临床应用价值。方法对114例患者进行3D CE MRA检查。3D CE MRA主要参数为重复时间5ms,回波时间1.5ms,翻转角50°。增强对比剂为钆-喷替酸萄甲胺(Gd-DTPA),剂量0.3mmol/kg,平均30ml。每次扫描时间为15s左右,不间断重复采集3次。原始图像先进行减影处理,再进行最大信号强度投影(MIP)重建。增强扫描前先行横断位FSE序列T1WI、T2WI。CE MRA扫描后行横断位FSE T1WI。可疑撕裂口处行Cine序列。重点观察主动脉及其分支显示情况,以及主动脉有无动脉瘤、夹层、扩张或缩窄以及病变是否累及其分支。结果114例的主动脉及其主要分支均显示清晰,且均达到诊断要求。其中包括主动脉病变83例(动脉瘤32例,夹层动脉瘤37例,主动脉其他病变14例),肝癌9例(门静脉癌栓3例),布加综合征1例(肝段下腔静脉狭窄),胸腹腔肿瘤4例(可见局部血管受压),肾癌2例(肾动脉增粗),正常15例。结论3DCEMRA是一种对评价主动脉病变的有效微创伤技术。Objective To evaluate the technique and assess the value of clinical applications of 3D dynamic contrast-enhanced MR angiography （3D CE MRA）. Methods 114 patients were performed MRI examination with 3D CE MRA （repetition time 5 ms, echo time 1.5 ms, flip angle 500） after intravenous injection of Gd-DTPA （0.3 mmol/kg body weigh）. The source images was subtracted from mask images followed by maximum intensity projection （MIP） and multiplanner reconstruction （MPR）. Axial FSE T1WI,T2WI scans were obtained before contrast, and FSE axial T1WI obtained after contrast. Cine sequence was performed at tear site. The focus is whether aorta is dissected or there is aneurysm or dilating or narrowing and whether its branches is involved. Results Aorta and its branches were viewed clearly with 3D CE MRA in all patients. The results are as follows： aneurysm （n=32）, aortic dissection （n=37）, other aortic disease （n=14）, portal vein thromb （3 in 9 patients with hepatic cancer）,Bud-chiari malformation （n=1）, aortic shift （n=4）, renal artery dilation（n=2,renal cancer）, and normal aorta（n=15）. Conclusion 3D CE MRA is a reliable and robust technique for large vessels imaging.

关 键 词：大血管 磁共振 血管造影 

分 类 号：R543.104[医药卫生—心血管疾病]