吡罗昔康凝胶与双氯芬酸钠凝胶治疗骨关节炎的随机对照试验  

Therapeutic Effects of Piroxicam Gel and Diclofenac Sodium Gel on Osteoarthri tis

作　　者：黄丽萍[1] 刘忠[1] 徐建华[2] 孙桂华 

机构地区：[1]武汉市第四医院,430030 [2]安徽医大附属医院

出　　处：《药物流行病学杂志》1997年第4期205-206,共2页Chinese Journal of Pharmacoepidemiology

摘　　要：目的:考察吡罗昔康凝胶(pir)与双氯芬酸钠凝胶(dic)治疗骨关节炎的疗效和不良反应.对象和方法:120例骨关节炎患者,随机分为吡罗昔康凝胶组 60例和双氯芬酸钠凝胶组 60例,分别采用局部涂擦的给药办法,每天 3～4次,14d为一疗程.结果:pir和dic治疗骨关节炎的总有效率分别为7O.0%和68.3%,经统计学处理无差异;耐受性两药相近,不良反应以轻度胃肠道反应和局部皮肤反应为主.To compare the therapeutic effects between piroxicam gel and diclofenac sodium gel in treatment of osteoarthritis, piroxicam gel and diclofenac sodium gel were applied to the patients with os-teoarthritis (qid, 2 weeks, n=120). Our results revealed a total effective rates of 70% for piroxicam gel and 68.3% for diclofenac sodium gel and no statistical difference was found (P>0.05). Adverse actions of both groups, mainly gastrointestinal reaction and local skin rash, were mild and tolerance to the two drugs were similar.

关 键 词：吡罗普康凝胶 双氯芬酸钠凝胶 骨关节炎 治疗 

分 类 号：R684.305[医药卫生—骨科学]