宫内节育器与异位妊娠发生率的关系  

Relationship between IUD and incidence of ectopic pregnancy

作　　者：刘萍 李小利 

机构地区：[1]广东省广州市番禺区妇幼保健院,广东广州511400

出　　处：《中国妇幼健康研究》2008年第3期249-250,共2页Chinese Journal of Woman and Child Health Research

摘　　要：目的探讨宫内节育器与异位妊娠发生率的关系。方法通过流行病学调查，对2001-2006年具有广州番禺区市桥城区户口的育龄妇女按年龄段分组，并对放置与未放置宫内节育器妇女的异位妊娠发生率进行比较；同时按放置不同种类宫内节育器妇女发生异位妊娠情况进行统计评价。结果20-30岁、31-40岁、41-50岁放置宫内节育器的妇女异位妊娠发生率分别为1.41％、1.23％和0.51％，未放置宫内节育器的妇女异位妊娠发生率分别为1.50％、1.29％和0.50％，经统计学比较无显著性差异（P〉0.05）。妇女异位妊娠发生率放置金属圆环节育器为1.37％（458／33510）、V型节育器为1.26％（51／4040）、TCu-200为0.58％（27／4623）、TCu-380A为0．51％（49／9565）、固定式宫内节育器（吉妮环）为0．36％（2／556），其中放置金属圆环与V型节育器妇女异位妊娠发生率比较无显著性差异（P〉0．05），放置金属圆环与放置TCu-200、TCu-380A和吉妮环这3种带铜节育器妇女的异位妊娠发生率相比较有显著性差异（分别为X^2=19．881，P〈0．01；X^2=46．710，P〈0．01；X^2=4.226，P〈0．05）。结论官内节育器并未增加异位妊娠的危险性；放置带铜节育器异位妊娠发生率最低，不但阻止了宫内妊娠，也预防了异位妊娠的发生。Objective To investigate relationship between intrauterine device （IUD） and incidence of ectopic pregnancy. Methods In epidemiological investigation method, the women of childbearing age with resident certification of Panyu district were divided into three age groups and the incidence rate of ectopic pregnancy （EP） of the women with or without IUD in different age groups over a period from 2001 to 2006 was compared. Results The incidence rates of ectopic pregnancy of women with IUD in the 20-30 years old group, the 31-40 years old group and the 41 -50 years old group were 1.41% and 1.23% and 0.51% , respectively, while those of the women without IUD in the three age groups were 1.50%, 1.29% and 0. 50%, respectively, and there were no statistically significant differences （ all P 〉 0.05）. The ectopic pregnancy rates of women with round metallic IUD, V-shaped IUD, TCu-200IUD, TCu-380 IUD and Gynefix IUD were 1.37% （458/33 510）, 1.26% （51/4 040）, 0.58% （ 27/4 623 ）, 0.51% （49/9 565 ） and 0.36% （ 2/556）, respectively. Of which, between women with round metallic IUD and women with V-shaped IUD, there was no statistically significant difference in the EP rate （P 〉 0.05）. While between women with round metallic IUD and women with copper-containing IUDs, including TCu-200 IUD, TCu-380 IUD and Gynefix IUD, there were statistically significant differences in EP incidence rate （X^2-19.881 ,P 〈0.01 ; X^2=46.710, P 〈 0.01 ; X^2= 4.226, P 〈 0.05, respectively）. Conclusion IUD application does not increase risk of EP. The EP incidence rate of those women with copper-containing IUDs is the lowest, not only preventing intrauterine pregnancy, but also decrease the EP rate.

关 键 词：金属节育器 带铜节育器 发生率 异位妊娠 

分 类 号：R169.41[医药卫生—公共卫生与预防医学]