日本血吸虫病重疫区人群B超流行病学调查  

EPIDEMIOLOGICAL SURVEY ON HUMAN SCHISTOSMIASIS BY B-ULTRASOUND IN HYPER-ENDEMIC AREA,SICHUAN

作　　者：张桂盛[1] 周国兴[1] 邱东川[1] 黄启华[1] 文松[1] 吴子松[1] 毛勇[1] 张奕[1] 崔丽娜 山建中 蔡新平 

机构地区：[1]四川省寄生虫病防治研究所,成都610041 [2]眉山县血防站

出　　处：《实用寄生虫病杂志》1997年第4期161-164,共4页Journal of Practical Parasitic Diseases

基　　金：UNDP/World Bank/WHO/TDR的资助

摘　　要：按照世界卫生组织1990年开罗会议制定的”超声诊断在血吸虫病应用中的试行标准化方法”，在日本血吸虫所致肝脏病理损害超声图上可显示明确特征性的基础上，作者于1992年在血吸虫病重疫区的两个自然村，整群抽样1004例村民进行腹部B超检查。结果显示肝实质有不同程度改变者639人（63．6％），其中肝实质改变为I级者454人（45．2％）、Ⅱ级131人（13．0％）、Ⅲ级54人（5．4％）。肝实质超声图显示异常者中粪检、免疫学检查、直检阳性者与各项检测阴性者进行比较，两组超声异常率分别为74．1％及9．8％（P＜0．01），而非流行村200例配对对照组未发现1例超声异常。另通过对成人和儿童肝、脾、门静脉内径的超声测量结果表明，判断异常的标准值尚有待进一步探讨。本研究再次证实了B超在现场应用中，对人群血吸虫病患病率的评估和防治效果的判断具有实用价值，可作为该病流行病学调查的一种较好的方法。In 1992, a cluster sample of 1004 villagers from 2 natural villages in hyper-endemic area, Sichuan was examined abdominally by B-ultrasound according to the'Meeting on ultrasonography in schistosomiasis proposal for a practical guide to the standardized use of ultrasound in the assessment of pathological changes, Cairo, Egypt'held by WHO/TDR for exploring the practical value on B-ultrasound liver damage and schistosomiasis epidemiology.The results showed that specific liver Parenchyma changes were detected in 639 cases (63.6% ) in which 454 cases (45.2% )belonged to Grade I changes, 131 ase(13.0% ) Grade Ⅱ and 54 care (5.4% )Grade Ⅲ .623(74.1% )out of 841 cases with positive findings in stool , or serodiagnosis or rectal examination and only 16(9.8% )out of 163 cases negative in all examinations showed significant differences(P < 0.01 ) in specilic B-ultrasound findings.In control group containing 200 matched-pair cases from non-endemic villages, no peecific findings were detected.In addition, were detected. In addition, the B-ultrasound measurement of liver, spleen and portal vein internal diameter indicated that the normal value for assessing the damage remained to be studied.The study confirmed that B-ultrasound examination could be applial for epidemiological survey in schistosomiasis japonica endemic areas.

关 键 词：B超 日本血吸虫病 人群感染 流行病学 

分 类 号：R532.210.1[医药卫生—内科学]