分子印迹技术用于蛋白质的识别  

Molecular Imprinting Technology for Protein Recognition

作　　者：盖青青[1] 刘秋叶[1] 何锡文[1] 李文友[1] 陈朗星[1] 张玉奎[1] 

机构地区：[1]南开大学化学系

出　　处：《化学进展》2008年第6期957-968,共12页Progress in Chemistry

基　　金：国家重点基础研究发展计划(973)项目(No2007CB914101);国家自然科学基金项目(No20675040);天津市自然科学基金项目(No06YFJMJC02800,07JCYBJC00500)资助

摘　　要：分子印迹技术是一种新型的高效分离技术。合成含识别蛋白质的分子印迹聚合物具有巨大的应用价值,又极具挑战性,已成为许多分子识别领域工作者的研究热点。本文总结了近10年来该领域的研究进展,讨论了已有不同方法的发展状况以及相对优缺点,阐明了其可能发展的方向和前景。Molecular imprinting is an effective technique for the creation of recognition sites in a polymer network. Protein imprinting has been a focus for many chemists working in the area of molecular recognition, since the creation of synthetic polymers that can specifically recognize proteins is challenging and extremely applicably valuable. This review gives an overview of the progress about molecularly imprinted polymers （MIPs） for protein recognition in the recent decade, discusses different approaches developed, underlines their relative advantages and disadvantages and highlights trends and possible future directions.

关 键 词：蛋白质 分子印迹技术 分子识别 

分 类 号：O658.9[理学—分析化学] O641.3[理学—化学]