外周血涂片检出幼稚红细胞临床意义探讨  

A discussion of the clinical significance of the immature red blood cells detected in peripheral blood smear

作　　者：刘杰[1] 杨晓春[1] 郝维敏[1] 

机构地区：[1]安徽省宿州市立医院检验科,234000

出　　处：《淮海医药》2008年第4期302-304,共3页Journal of Huaihai Medicine

摘　　要：目的通过对外周血涂片幼稚红细胞检出率分析,探讨血液肿瘤性疾病与血液非肿瘤性疾病外周血涂片出现幼稚红细胞的临床意义。方法对2001年1月～2007年10月我院992例骨髓细胞学检查患者同时做外周血涂片检查。血涂片计数100个白细胞并分类,幼稚红细胞检出率以100个白细胞同时发现幼稚红细胞数(即幼红细胞数/100个WBC)表示。结果在992例骨髓和外周血同步检查中,外周血涂片检出幼稚红细胞122例。血液肿瘤性疾病外周血涂片幼红细胞检出率为32.3%,血液非肿瘤性疾病外周血涂片幼红细胞检出率为9%,两者外周血涂片幼红细胞检出率比较差异有显著性(P<0.05)。结论外周血涂片检出幼稚红细胞对血液肿瘤性疾病与血液非肿瘤性疾病的诊断与鉴别诊断有一定的临床意义,血液中出现不明原因的幼红、幼粒细胞应引起重视,严密随访。Objective To discuss the clinical significance of the immature red blood cells detected in peripheral blood smear of neoplastic hematologic disorder and non-neoplastic heamatologic disorder through the analysis of the detection rate of the immature red blood cells in peripheral blood smear. Methods Peripheral blood smears of 992 patients were simultaneously examined who had made a myelocytology check in our hospital （Jan. 2001 - Oct. 2007）. After counting and classification of 100 white blood cells,the detection rate of the immature red cells was demonstrated by the detection of the immature red blood cell counts of 100 white blood cells （immature RBC counts/100 WBC）. Results 122 examples were detected to have immature red blood cells in peripheral blood smear of 992 patients who simultaneously had the examination of myelocytology and periphera1 blood smear. The detection rate of the immature red blood cells in peripheral blood smear of neoplastic hematologic disorder patients was 32.3%. The detection rate of the immature rad blood cells in peripheral blood smear of non-neoplastic hematologic disorder patients was 9%. There was significant disparation between them （ P 〈 0. 005 ）. Conclusion There is certain clinical significance to the diagnosis and the differential diagnosis between neoplastic hematologic disorder and non-neoplastic hematologic disorder by detecting immature red blood cells in peripheral blood smear. Reconstruction should be evoked and follow-up visit be taken when immature red blood cells and immature granular cells in nubibus are found in peripheral blood.

关 键 词：血液病 幼稚红细胞 幼稚粒细胞 血涂片 诊断 鉴别 

分 类 号：R446.11[医药卫生—诊断学]