中药对脑微血管内皮细胞影响的研究进展  

Effects of Chinese Herbs on Brain Microvascular Endothelial Cells Function

作　　者：赵琳[1] 郭虹[1] 刘洋[1] 张萌[1] 胡利民[1] 康立源[1] 

机构地区：[1]天津中医药大学中医药研究院天津市中药药理重点实验室省部共建教育部方剂学重点实验室,天津300193

出　　处：《辽宁中医杂志》2008年第6期950-951,共2页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973)项目课题(2005CB523404);国家自然基金课题(30572348);教育部高校全国优博论文作者专项资金资助项目(200365);云南省省院省校科技合作计划(2006YX03)

摘　　要：脑微血管内皮细胞不仅仅具有屏障特性,而且还具有多种分泌功能,因此微血管内皮细胞的损伤与脑血管疾病的发生、发展有着密切的关系,也为研究中药防治脑血管疾病的机制提供了基础。近年来,围绕中药减轻脑血管疾病过程中微血管内皮细胞损伤,展开了很多研究。仅从细胞的屏障特性、细胞氧化损伤、细胞的分泌功能等几个方面综述了中药对体外培养脑微血管内皮细胞影响的研究进展。The brain microvascular endothelial cells have a lot of characters, they not only act as an barrier, but also can se- crete much cytokine. So there may be a close relationship between the injury of the BMEC and the occurrence,development of the cerebrovascular disease,and also offers a basis for the mechanism of the therapy of the cerebrovascular disease by the TCM. In re- cent years,more and more researchers begin to pay attention to the effect of the traditional Chinese medicine （TCM） in the dam- age of the microvascular endothelial cell in the cerebrovascnlar disease. This text overviews the advancement of the effect of the TCM on the BMEC, from the different aspects of the barrier character, excrete character, et al.

关 键 词：中药 脑微血管内皮细胞 血脑屏障 

分 类 号：R277.7[医药卫生—中医学]