制备中空海藻酸钙胶囊新方法的研究  

A New Method for the Preparation of Alginate-Ca capsule with Liquid Core

作　　者：陈国[1] 黄世丰[1] 

机构地区：[1]华侨大学工业生物技术福建省高等学校重点实验室,泉州362021

出　　处：《山西大学学报（自然科学版）》2008年第1期119-123,共5页Journal of Shanxi University(Natural Science Edition)

基　　金：福建省青年人才项目(2006F3080);华侨大学高层次人才科研启动基金(06BS214)

摘　　要：中空海藻酸钙胶囊是将CaCl2溶液反滴入海藻酸钠溶液后,在液滴表面胶凝成膜而成.研究了一种新的Alginate/(NaCS+CaCl2)体系中空海藻酸钠胶囊的制备方法.重点探讨了反应时间、滴加速度、海藻酸钠溶液浓度、NaCS和CaCl2溶液浓度等参数对制得胶囊的直径、膜厚和机械强度等性质的影响.并确定了中空海藻酸钙胶囊的制备条件:1%(W/V)的海藻酸钠溶液,10%(W/V)的CaCl2溶液,2%(W/V)的NaCS溶液,180滴/min的滴加速度和10 min的凝胶反应时间.Intra-hollow Ca-alginate capsule is the development of traditional Ca-alginate bead. It was prepared by membrane formation on the interface through adding droplets of CaC12 solution into sodium alginate solution. We designed a novel system of Alginate/（NaCS＋CaC12） for preparation of intra-hollow Ca-alginate capsule and studied the effects of operation conditions gelation time, dropping velocity and （concentrations of CaC12,NaCS or sodium alginate） on the diameter,membrane thickness and compression intensity of the capsules. The optimal operation conditions for capsule preparation were determined at 100 g/L CaC12 solution, 10 g/L sodium alginate solution, 12 g/L sodium cellulose sulfate solution,dropping velocity of 180 droplets/rain and gelation time for 10 min.

关 键 词：海藻酸钠 中空胶囊 纤维素硫酸钠 胶囊特性 

分 类 号：O631[理学—高分子化学]