经门静脉灌注丹参注射液治疗肝硬化腹水的研究  

Study on the treatment for hepatocirrhosis ascites with infusion of Danshen injection via portal vein

作　　者：黄荣柏[1] 胡锡琮[1] 李敏江[1] 莫小勤[1] 王克净[1] 黄新全[1] 谢斌[1] 

机构地区：[1]广西中医学院附属瑞康医院,广西南宁530011

出　　处：《现代中西医结合杂志》2008年第19期2924-2925,共2页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：广西壮族自治区卫生厅科研课题(Z2005091);广西中医学院重点科研课题(ZD2005014)

摘　　要：目的探讨经门静脉灌注丹参注射液治疗肝硬化腹水的临床疗效。方法将247例肝硬化腹水患者随机分为3组:A组经门静脉注入丹参注射液,B组由肢体周围静脉滴入丹参注射液,C组经门静脉注入生理盐水。各组均按肝脏储备功能Child-Pugh分级统计疗效。结果A组中B级和C级显效率、好转率、总有效率与B组和C组比较均有极显著性差异(P均<0.01)。结论经门静脉灌注丹参注射液治疗肝硬化腹水具有良好的临床疗效。Objective It is to observe the clinical curative effect of Danshen injections via portal vein on hepatocirrhosis ascites. Methods 247 patients with cirrhotic ascites were randomly divided into 3 groups： group A was accepted infusion of Danshen injection via portal vein, group B accepted Danshen injection via peripheral vein, group C accepted normal saline via portal vein. The curative effect was evaluated with liver reservation function of Child pugh classification. Results The total, improving and remarkable effective rates in group A were obviously higher than that in group B and C. The differences were significant （P all〈0.01 ）. Conclusion Infusion of Danashen injection via portal vein has a good curative effect on hepatocirrhosis ascites.

关 键 词：肝硬化腹水 丹参注射液 门静脉 

分 类 号：R657.31[医药卫生—外科学]