红景天对血管性痴呆大鼠行为学影响的实验研究  

To Study the Effects of Rhodiola Herb Against Behavior of Vascular Dementia Rat Lnduced by Chonic Cerebral

作　　者：吴栋[1] 杨发明[1] 樊改英[1] 燕浩杰[1] 

机构地区：[1]山西医科大学第二医院

出　　处：《光明中医》2008年第6期727-729,共3页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：目的:研究红景天对血管性痴呆大鼠行为学的影响,明确红景天的治疗VD作用。方法:采用Morris水迷宫对大脑前动脉供血不足大鼠血管性痴呆模型检测定位航行试验、空间搜索试验。结果:造模组与对照组相比认知能力明显下降(P<0.01),治疗组与模型组相比认知能力明显改善(P<0.01)。结论:血管性痴呆大鼠给予中药红景天后,可保护神经细胞,促进脑功能的恢复,从而改善大鼠学习记忆能力。Objective：To study the effects of Rhodiola herb against behavior of vascular dementia rat induced by chonic cerebral. Methods： vascular dement model was formed by adopting the permanent occlusion of bilateral carotid arteries in wistar rats to produce the forebrain ischemia. And the protective effect of Rhodiola herb was observed. Cognitive ability of rats were studied with the Morris water maze. Results ： Vascular dement model may decrease ability（ P 〈 0.01 ）, Rhodiola herb significant alleviated cognitive ability（ P 〈 0.01 ）. Conclusion： Rhodiola herb may improve cognitive ability in Vascular Dementia rats.

关 键 词：红景天 学习记忆 水迷宫 血管性痴呆 

分 类 号：R285.5[医药卫生—中药学]