基于时间分辨反射测量的混浊介质光学参数计算方法  

Method for Determining Optical Properties of Turbid Media Based on Time-Resolved Reflection Measurement

作　　者：高峰[1] 和慧园[1] 马烝[1] 

机构地区：[1]天津大学精密仪器与光电子工程学院,天津300072

出　　处：《天津大学学报》2008年第6期757-761,共5页Journal of Tianjin University(Science and Technology)

基　　金：国家重点研究发展计划(973)资助项目(2006CB705700);国家自然科学基金资助项目(60578008;60678049);天津市自然科学基金资助项目(07JCYBJC06600)

摘　　要：发展了一种基于时间分辨反射测量技术的混浊介质光学参数重构方法.采用半无限空间扩散方程解析解卷积时间定标测量曲线获得模拟时间扩展曲线,将此与基于时间相关单光子计数技术实测的全时间分辨曲线进行归一化拟合;在对一个已知光学参数的定制模型验证的基础上,通过对4个参数未知的混浊介质进行测量,显示了方法的可行性和有效性.A method for determining the optical properties in turbid medium is developed based on time-resolved reflection measurement. First, a model for predicting the time spread profile is obtained by convolving the analytic solution to the diffusion equation on a semi-infinite turbid medium with the measured impulsive response function of the system. Then, the model is normalized fitted to a full-time-resolved profile that is measured using a time-correlated single photon counting system. Finally, the feasibility and effectiveness of the method are validated by measuring a model with given optical properties, and further demonstrated by determining four samples with unknown optical properties.

关 键 词：时间相关单光子计数 时间分辨反射测量 扩散方程 最小二乘优化 吸收系数 约化散射系数 

分 类 号：R338.8[医药卫生—人体生理学]