胎儿纤维连接蛋白测定联合宫颈长度测量对预测早产的比较  

Comparison of examination premature labor between level of fetus fable unit protein plus length of cervix

作　　者：刘津予 卢光荣 

机构地区：[1]河南省新乡市第二人民医院,453002 [2]河南省新乡市妇幼保健院

出　　处：《中国实用医药》2008年第17期7-8,共2页China Practical Medicine

摘　　要：目的比较胎儿纤维连接蛋白(fFN)测定联合经阴道超声测量宫颈长度与单纯测量宫颈长度对预测早产的敏感性和特异性。方法对有先兆早产症状的109例孕妇随机分为两组,宫颈组仅经阴道超声测量宫颈长度,联合组行阴道超声测量宫颈长度的同时做阴道后穹隆分泌物fFN测定。比较两组对预测早产的敏感性和特异性,进行统计学处理。结果宫颈组49例中经阴道超声测量宫颈长度≤26 mm的孕妇有37例,早产16例,阳性预测值43.2%,敏感性32.7%,阴性预测值56.8%,特异性36.4%。联合组中行阴道超声测量宫颈长度≤26 mm的同时做阴道后穹隆分泌物fFN测定(+)的有56例,早产51例,阳性预测值91.1%,敏感性85%,阴性预测值8.9%,特异性44.4%。比较两组阳性预测值、敏感性,差异有统计学意义(P<0.01),比较两组特异性,差异无统计学意义(P>0.05)。结论经阴道超声测量宫颈长度联合阴道后穹隆分泌物fFN测定对于预测早产的敏感性高于单纯宫颈长度测量。Objective To compare sensitivity and specificity of level of fetus fable unit protein plus length of cervix and simple length of cervix preliminary examination premature labor. Method 109 gravida with presumed of premature labor were randomly divided into two groups. Collect group was diagnosed with the level of fetus fable unit protein plus the length of cervix. Cervix group was diagnosed with simple length of cervix. Both sensitivity and specificity were compared. Results In collect group there were positive diagnosis of 56 cases, actual premature labor 51 cases, the sensitivity was 85% , positive premature was 91.1%, specificity was 44.4%, There were positive diagnosis of 37 cases, actual premature labor 16 cases, the sensitivity was 32. 7% ,positive premature was 43.2% , specificity was 36.4% , in cervix group. There were statistical differences（ P 〈 0. 01 ） in sensitivity between two groups. There were no statistical differences （ P 〉 0. 05 ） in specificity between two groups. Conclusion The sensitivity of diagnosing premature labor with the level of fetus fable unit protein plus the length of cervix is higher than that with simple length of cervix.

关 键 词：纤维连接蛋白类 宫颈长度 早产 

分 类 号：R714.21[医药卫生—妇产科学] R816.4[医药卫生—临床医学]