河北省城、乡1～14岁儿童乙肝疫苗接种率及乙肝病毒携带状况比较  

COMPARISON ON HBV CARRYING STATUS AND HEPATITIS B VACCINE INOCULATION RATE AMONG CHILDREN AT THE AGE OF 1 TO 14 YEARS BETWEEN URBAN AREAS AND RURAL AREAS IN HEBEI PROVINCE

作　　者：韩彩芝[1] 马景臣[1] 齐顺祥[1] 田茶[1] 

机构地区：[1]河北省疾病预防控制中心,石家庄050021

出　　处：《现代预防医学》2008年第12期2344-2346,2349,共4页Modern Preventive Medicine

摘　　要：[目的]比较研究河北省城、乡监测点1～14岁儿童乙肝疫苗接种率及乙肝病毒携带状况。[方法]采取多阶段整群随机抽样的方法,调查3个城市监测点和5个农村检测点1～14岁儿童1736人。[结果]1～14岁儿童乙肝疫苗接种率、首针及时接种率、全程接种率和抗-HBs阳性率城市高于农村。城、乡儿童HBsAg阳性率分别为0.63%、1.67%,抗-HBc阳性率为1.32%、4.78%;乙肝疫苗全程及时接种与未及时接种儿童的HBsAg阳性率比较P﹤0.05;乙肝疫苗全程接种的城市与农村儿童HBsAg阳性率比较P﹤0.01,均有统计学意义。[结论]农村儿童HBsAg阳性率和抗-HBc阳性率较高主要是由于乙肝疫苗接种率、首针及时接种率和全程接种率较低造成,须进一步加强农村儿童乙肝疫苗免疫接种工作。[Objective] To compare HBV coverage and hepatitis B vaccine inoculation rate among children at the age of 1 to 14 years between urban and rural monitoring sites in Hebei province. [ Methods] By stratified cluster randomize sampling, 1736 children at the age of 1 to 14 years were selected from 3 urban monitoring sites and 5 rural monitoring sites. [ Results] The Hepatitis B vaccine inoculation rate, timely-birth dose inoculation rate, hepatitis B vaccine inoculation rate for the whole vaccination course and positive rate of anti-HBs among children at the age of 1-14 years in urban monitoring sites were higher than those in rural monitoring sites. The positive rate for HBsAg in urban children and rural chihlren were 0.63% and 1.67%, respectively, and for anti-HBe were 1.32% and 4.78%, respectively. The positive rate of HBsAg among children with timely course HBV vaccine inoculation showed significant difference with children with no-timely HVB vaccine inoculation （P 〈 0.05）. When compared with the rural children, the positive rate for HBsAg among urban children with course HBV vaccine inoculation showed significant difference （P 〈 0.05）. [Conclusion] The higher positive rates of HbsAg and anti-HBc among children in rural areas were due to the lower hepatitis B vaccine inoculation rate, timely-birth dose inoculation rate and course hepatitis B vaccine inoculaton rate. It is necessary to strengthen the HVB vaccine inoculation for rural children.

关 键 词：乙肝疫苗接种率 乙肝病毒感染 儿童 

分 类 号：R186[医药卫生—流行病学] R512.62[医药卫生—公共卫生与预防医学]